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-  2016 

帕金森病患者手指开合动作规律性的量化评估

DOI: doi:10.7507/1001-5515.20160157

Keywords: 手指开合动作测试, 帕金森病, 规律性, 量化评估, 近似熵, 样本熵

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Abstract:

临床上,手指开合动作测试是神经内科对帕金森病(PD)患者运动能力的一个常用检测项目,它主要从动作幅度、速度和规律性三个方面评价患者的手部精细运动能力。本文旨在关注PD患者手指开合动作规律性的量化评估,用惯性传感器单元采集测试对象在手指开合过程中食指和拇指的运动信号,计算近似熵(ApEn)和样本熵(SampEn)两个非线性动态指标,然后对计算结果进行统计分析。试验结果表明,两个指标不仅在病例组和对照组之间有较大差异,而且与临床医生给出的统一帕金森病评分量表(UPDRS)对应项评分有较高的相关性,说明两个指标均能够在一定程度上反映帕金森病患者手指重复性动作的受损程度,可以作为临床上对帕金森病患者运动能力评估的一种可靠方法

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