全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
-  2016 

丘脑底核深部脑刺激三维空间结构可视化

DOI: doi:10.7507/1001-5515.20160069

Keywords: 核磁共振影像, 深部脑刺激, 电极术中定位, 三维可视化

Full-Text   Cite this paper   Add to My Lib

Abstract:

深部脑刺激(DBS)电极植入的准确性直接决定着帕金森病患者深部脑刺激最终治疗效果。由于丘脑底核体积较小、边界不明显,术中核磁共振影像(MRI)分辨率低、电极伪迹大,而丘脑底核区域三维空间结构可视化将为医生提供直观和精准的定位信息。本文在标准脑图谱空间下对双侧丘脑底核刺激治疗的患者术前高分辨率和术中低分辨率核磁共振扫描影像进行配准融合,用阈值法自动确定横断面影像上的电极位置,并利用冠状面影像校验触点位置,重建完整深部脑刺激电极路径。利用标准图谱灰度信息分割丘脑底核及其附近重要核团,实现深部脑刺激电极植入路径重建与丘脑底核及其附近区域神经核团三维空间结构的可视化,为深部脑刺激术中定位提供定量直观信息,提高电极植入精度,并为术后程控刺激参数设置提供指导

References

[1]  1. KRACK P, BATIR A, VAN BLERCOM N, et al. Five-year follow-up of bilateral stimulation of the subthalamic nucleus in advanced Parkinson's disease[J]. N Engl J Med, 2003, 349(20) :1925-1934.
[2]  2. SCHUURMAN P R, BOSCH D A, BOSSUYT P M, et al. A comparison of continuous thalamic stimulation and thalamotomy for suppression of severe tremor[J]. N Engl J Med, 2000, 342(7) :461-468.
[3]  3. FRANK M J, SAMANTA J, MOUSTAFA A A, et al. Hold your horses:impulsivity, deep brain stimulation, and medication in parkinsonism[J]. Science, 2007, 318(5854) :1309-1312.
[4]  4. STANCANELLO J, MUACEVIC A, SEBASTIANO F, et al. 3T MRI evaluation of the accuracy of atlas-based subthalamic nucleus identification[J]. Med Phys, 2008, 35(7) :3069-3077.
[5]  5. TODA H, SAWAMOTO N, HANAKAWA T, et al. A novel composite targeting method using high-field magnetic resonance imaging for subthalamic nucleus deep brain stimulation[J]. J Neurosurg, 2009, 111(4) :737-745.
[6]  6. FONOV V, EVANS A C, BOTTERON K, et al. Unbiased average age-appropriate atlases for pediatric studies[J]. Neuroimage, 2011, 54(1) :313-327.
[7]  7. HORN A, KVHN A A. Lead-DBS:a toolbox for deep brain stimulation electrode localizations and visualizations[J]. Neuroimage, 2015, 107:127-135.
[8]  8. DALE A M, LIU A K, FISCHL B R, et al. Dynamic statistical parametric mapping[J]. Neuron, 26(1) :55-67.
[9]  9. SCH?NECKER T, KUPSCH A, KVHN A A, et al. Automated optimization of subcortical cerebral Mr imaging-atlas coregistration for improved postoperative electrode localization in deep brain stimulation[J]. AJNR Am J Neuroradiol, 2009, 30(10) :1914-1921.
[10]  10. GRACHEV I D, BERDICHEVSKY D, RAUCH S L, et al. A method for assessing the accuracy of intersubject registration of the human brain using anatomic landmarks[J]. Neuroimage, 1999, 9(2) :250-268.
[11]  11. VIDEEN T O, CAMPBELL M C, TABBAL S D, et al. Validation of a fiducial-based Atlas localization method for deep brain stimulation contacts in the area of the subthalamic nucleus[J]. J Neurosci Methods, 2008, 168(2) :275-281.
[12]  12. ANDRADE-SOUZA Y M, SCHWALB J M, HAMANI C, et al. Comparison of three methods of targeting the subthalamic nucleus for chronic stimulation in Parkinson's disease[J]. Neurosurgery, 2005, 56(2 Suppl):360-368.
[13]  13. KRAUTH A, BLANC R, POVEDA A, et al. A mean three-dimensional Atlas of the human thalamus:Generation from multiple histological data[J]. Neuroimage, 2010, 49(3) :2053-2062.
[14]  14. KLEIN A, ANDERSSON J, ARDEKANI B A, et al. Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration[J]. Neuroimage, 2009, 46(3) :786-802.
[15]  15. VAN DEN MUNCKHOF P, CONTARINO M F, BOUR L J, et al. Postoperative curving and upward displacement of deep brain stimulation electrodes caused by brain shift[J]. Neurosurgery, 2010, 67(1) :49-53.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133