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-  2015 

肺黏膜相关淋巴组织淋巴瘤23例临床分析

DOI: doi:10.7507/1671-6205.2015116

Keywords: , 淋巴瘤, 黏膜相关淋巴样组织

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Abstract:

目的探讨肺黏膜相关淋巴组织淋巴瘤的临床特征、诊断和治疗的方法。 方法收集23例肺黏膜相关淋巴组织淋巴瘤的临床表现、实验室检查、影像、诊断及治疗资料, 结合文献进行回顾性分析。 结果23例患者中, 男14例, 女9例; 年龄22~71岁, 中位年龄58岁; 体检发现7例, 其余15例有呼吸系统症状, 1例右肺叩诊实音。肺CT表现大片实变影10例、肿块影9例多伴有充气支气管征, 结节影10例、小片状网格影1例, 1例纵隔隆突下肿物; 1例患者胸腔缩小。免疫组化结果为CD20(+), cyclind-1(-), Ki-67指数介于5%~25%。10例患者采用化疗, 9例患者采用手术治疗, 其中1例患者手术加放疗, 3例未治疗。 结论肺黏膜相关淋巴组织淋巴瘤是一种低~中度恶性肿瘤, 临床起病隐匿, 多因体检和轻微呼吸道症状就诊。影像以肺实变影、肿块影伴充气支气管征为主。主要依靠病理及免疫组化检查确诊。目前治疗方案多样, 仍存争议, 有观察、手术、手术+化疗、单纯化疗、放疗等多种方案。预后极好, 生存期长

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