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-  2018 

慢性肺曲霉病基础疾病 108 例回顾性分析

DOI: doi:10.7507/1671-6205.201801004

Keywords: 慢性肺曲霉病, 慢性坏死性肺曲霉病, 肺结核, 支气管扩张症, 慢性阻塞性肺疾病, 糖尿病, 糖皮质激素

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Abstract:

目的 探讨慢性肺曲霉病(CPA)的基础疾病。 方法 回顾分析 2009 年 1 月至 2016 年 12 月原南京军区南京总医院收治的 CPA 患者的病历资料。 结果 总共收治 108 例 CPA 患者,其中 87 例有基础疾病,21 例无基础疾病。务农者比例 66.7%,该比例在无基础疾病组更高(85.7% 比 62.1%)。慢性坏死性肺曲霉病(CNPA)是最多见的类型(72/108,66.7%),在无基础疾病组中的占比高于基础疾病组(85.7% 比 62.1%),在系统性基础疾病组中的占比高于仅肺部基础疾病组(82.8% 比 51.7%)。慢性空洞性肺曲霉病均合并肺部基础疾病(24/108,22.2%)。基础疾病组以陈旧性肺结核(40.2%)、支气管扩张症(39.1%)、慢性阻塞性肺疾病(35.6%)等慢性肺部疾病多见。系统性因素以糖尿病(16.1%)和糖皮质激素使用(13.8%)多见。 结论 患者无论有无基础疾病均可发生 CPA。CNPA 是最常见的类型,其比例在无基础疾病及系统性基础疾病组更高。务农可能是 CPA 的危险因素。慢性肺部疾病是最常见的基础疾病。糖尿病和使用糖皮质激素是最常见的系统性因素

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