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-  2015 

低分子肝素对社区获得性肺炎临床疗效的影响

DOI: doi:10.7507/1671-6205.2015087

Keywords: 低分子肝素, 社区获得性肺炎, 临床疗效

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Abstract:

目的观察低分子肝素辅助治疗对社区获得性肺炎临床疗效的影响。 方法收集2013年1月至2015年3月哈尔滨医科大学附属第四医院呼吸内科住院的社区获得性肺炎患者共78例, 随机分为常规治疗组和低分子肝素联合治疗组。两组患者均给予抗感染、对症等治疗, 其中低分子肝素联合治疗组在常规抗生素治疗的基础上皮下注射低分子肝素, 每日1次, 7 d为一个疗程。所有患者统计年龄、性别、病情严重程度, 记录治疗前及治疗后第1 d、第3 d和第7 d的血常规、C反应蛋白、血沉的变化, 并统计分析两组上述3种指标随病情严重程度的变化。 结果与常规治疗组比较, 低分子肝素联合治疗组C反应蛋白、血沉在治疗后第3 d明显下降, 白细胞计数在治疗后第7 d明显下降, 差异均有统计学意义(P<0.05)。对于中、重度的社区获得性肺炎患者, 与常规治疗组比较, 低分子肝素联合治疗组C反应蛋白(治疗后第3 d)和白细胞计数(治疗后第7 d)均明显下降, 差异均有统计学意义(P<0.05)。 结论低分子肝素联合常规治疗可明显提高社区获得性肺炎的临床疗效

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