全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
-  2015 

阻塞性睡眠呼吸暂停低通气综合征患者疲劳与生活质量的相关性研究

DOI: doi:10.7507/1671-6205.2015017

Keywords: 阻塞性睡眠呼吸暂停综合征, 疲劳, 生活质量, 多维疲劳量表

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的评估阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的疲劳情况, 探讨其影响因素以及疲劳与生活质量的关系。 方法连续纳入2010年12月至2011年3月在四川大学华西医院睡眠中心行多导睡眠图(PSG)检查确诊的169例OSAHS患者和78例非OSAHS患者(对照组), 用多维疲劳量表(MFI)评估疲劳, 用Epworth嗜睡量表(ESS)评估白天过度嗜睡, 用睡眠困扰对日常生活影响问卷(FOSQ)评估生活质量。 结果OSAHS患者组的疲劳程度重于对照组(51.06±13.36比44.82±9.81, P<0.001), 不同程度OSAHS患者的疲劳程度无明显差异(P>0.05)。疲劳与ESS评分、总睡眠间期时间、血氧饱和度低于90%时间占总睡眠时间百分比呈正相关(r值分别为0.210、0.156、0.153, P<0.05), 与平均血氧饱和度呈负相关(r=-0.171, P<0.05)。疲劳程度与生活质量的各个维度呈负相关(P<0.01)。 结论OSAHS患者较对照组存在更严重的疲劳, 疲劳可显著影响OSAHS患者生活质量, 其影响大于白天过度嗜睡

References

[1]  9. Bailes S, Libman E, Baltzan M, et al.Fatigue:the forgotten symptom of sleep apnea.J Psychosoma Res, 2011, 70:346-354.
[2]  15. Sharafkhaneh A, Sharafkhaneh H, Bredikus A, et al.Effect of atrial overdrive pacing on obstructive sleep apnea in patients with systolic heart failure.Sleep Med, 2007, 8:31-36.
[3]  16. Bradley TD, Floras JS.Sleep apnea and heart failure:PartⅠ:obstructive sleep apnea.Circulation, 2003, 107:1671-1678.
[4]  17. Hossain JL, Ahmad P, Reinish LW, et al.Subjective fatigue and subjective sleepiness:two independent consequences of sleep disorders? J Sleep Res, 2005, 14:245-253.
[5]  18. 阳书坤, 余勤, 张佳宾, 等.阻塞性睡眠呼吸暂停低通气综合征患者认知功能和生活质量的关系.中国心理卫生杂志, 2008, 22:133-136.
[6]  19. 魏兵, 聂秀红, 张连国, 等.OSAHS患者认知功能的变化与生活质量的关系.临床肺科杂志, 2009, 14:1610-1612.
[7]  20. 张晓雯, 蔡晓岚, 潘新良, 等.阻塞性睡眠呼吸暂停低通气综合征患者生活质量分析.山东大学学报(医学版), 2007, 45:97-100.
[8]  21. 刘松, 陈颖, 翟慧, 等.中重度阻塞性睡眠呼吸暂停低通气综合征患者生活质量评价及持续气道正压治疗作用.医学临床研究, 2011, 28:1841-1844.
[9]  22. 马丹, 刘辉国, 艾永循, 等.生活质量评价在阻塞性睡眠呼吸暂停综合征患者临床诊断中的作用.华中科技大学学报, 2007, 36:380-384.
[10]  23. 鲁丹.老年SAS患者生存质量及其影响因素分析.中国医药导刊, 2011, 13:226-228.
[11]  24. Wattanachai C, Louise M, Ludi F, et al.Fatigue, tiredness, and lack of energy improve with treatment for OSA.J Clin Sleep Med, 2009, 5:222-227.
[12]  2. Kales A, Caldwell AB, Cadieux RJ, et al.Severe obstructive sleep apnea-Ⅱ:Associated psychopathology and phychosocial consequences.J Chronic Dis, 1985, 38:427-434.
[13]  3. Kales A, Cadieux RJ, Bixler EO, et al.Severe obstructive sleep apnea-Ⅰ:Onset, clinical course, and characteristics.J Chronic Dis, 1985, 38:419-425.
[14]  7. Reeves WC, Wagner D, Nisenbaum R, et al.Chronic fatigue syndrome-a clinically empirical approach to its definition and study.BMC Med, 2005, 3:19.
[15]  1. Chervin RD.Sleepiness, fatigue, tiredness, and lack of energy in obstructive sleep apnea.Chest, 2000, 118:372-379.
[16]  4. 中华医学会呼吸病学分会睡眠呼吸病学组.睡眠呼吸暂停低通气综合征诊治指南(草案).中华内科杂志, 2003, 42:594-597.
[17]  5. Nater UM, Wagner D, Solomon L, et al.Coping styles in people with chronic fatigue syndrome identified from the general population of Wichita, KS.J Psychosom Res, 2006, 60:567-573.
[18]  6. Natelson BH, Weaver SA, Tseng CL, et al.Spinal fluid abnormalities in patients with chronic fatigue syndrome.Clin Diagn Lab Immunol, 2005, 12:52-55.
[19]  8. Robert NA, Kenneth L, Sharon L, et al.Daytime functioning in obstructive sleep apnea patients:exercise tolerance, subjective fatigue, and sleepiness.Appl Psychophysiol Biofeedback, 1998, 23:207-217.
[20]  10. Bardwell WA, Moore P, Ancoli-Israel S, et al.Fatigue in obstructive sleep apnea:driven by depressive symptoms instead of apnea severity? Am J Psychiatry, 2003, 160:350-355.
[21]  11. Amnow WS.Cardiovascular manifestations seen in obstructive sleep apnea.Compr Ther, 2007, 33:82-86.
[22]  12. Peker Y, Carlson J, Hedner J.Increased incidence of coronary artery disease in sleep apnea:a long term follow-up.Eur Respir J, 2006, 28:596-602.
[23]  13. Garrigne S, Pèpin JL, Defaye P, et al.High prevalence of sleep apnea syndrome in patients with long-term pacing:the European Multicenter Polysomnographic Study.Circulation, 2007, 115:1703-1709.
[24]  14. Nieto FJ, Young TB, Lind BK, et al.Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study.Sleep Heart Health Study.JAMA, 2000, 283:1829-1836.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133