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-  2017 

营养不良筛选评分在机械通气的慢性阻塞性肺疾病急性加重患者中的应用价值

DOI: doi:10.7507/1671-6205.201609042

Keywords: 营养不良, 体重指数, 机械通气, 慢性阻塞性肺疾病

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Abstract:

目的 探讨营养不良筛选评分(MST)在有创机械通气(IMV)的慢性阻塞性肺疾病(简称慢阻肺)急性加重患者中的应用价值。 方法 采用单中心回顾性观察研究。纳入广州医科大学附属第一医院重症医学科自 2015 年 1 月 1 日到 2016 年 6 月 30 日收治的主要诊断为慢阻肺急性加重的患者,根据入 ICU 时 MST 评分分为营养不良高风险组(≥2分)和营养不良低风险组(<2 分)。主要比较两组患者的 ICU 病死率、住院病死率、有创通气时间、ICU 停留时间、48 h ICU 重返率,并同时比较两组一般资料以及入 ICU 时的生化指标。 结果 共纳入符合标准的患者 101 例,其中营养不良高风险组 77 例,营养不良低风险组 24 例。两组间患者性别( χ 2=1.882, P=0.172)、年龄( t=1.091, P=0.33)、急性生理学和慢性健康状况评分系统Ⅱ评分( t=1.475, P=0.16)比较,差异无统计学意义;营养不良高风险组患者体重指数( t=2.887, P=0.004)以及血淋巴细胞计数水平( t=3.402, P<0.001)均显著低于营养不良低风险组;而血红蛋白( t=0.817, P=0.36)、白蛋白( t=0.706, P=0.44)、前白蛋白( t=1.782, P=0.08)以及降钙素原( t=1.296, P=0.17)等生化指标在两组间比较,差异无统计学意义;营养不良高风险组患者 IMV 时间( χ 2=2.181, P=0.035)和 ICU 停留时间( χ 2=2.364, P=0.02)显著高于营养不良低风险组患者;两组间 ICU 病死率( χ 2=0.212, P=0.645),住院病死率( χ 2=0.212, P=0.645)以及 48 h ICU 重返率( χ 2=1.656, P=1.0)比较,差异无统计学意义。 结论 MST 评分是在 ICU 内评价需要 IMV 的慢阻肺急性加重患者营养不良风险的一个简便有效工具,MST 评分≥2 分提示患者需要更长的通气时间和 ICU 停留时间

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