全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
-  2017 

基于 CT 定量评估的肺气肿危险因素的 Logistic 回归分析

DOI: doi:10.7507/1671-6205.201612039

Keywords: 计算机体层成像, 肺气肿, 定量, Logistic 回归分析

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的 探讨低剂量 CT 筛查人群中肺气肿的发生率,并对相关危险因素进行回归分析。 方法 对 1 175 例参与低剂量 CT 筛查并完成问卷调查的志愿者进行肺气肿 CT 定量分析,统计肺气肿的检出率。整理问卷资料,并将问卷中各项因素进行非条件 Logistic 回归分析。 结果 1 175 例志愿者中,共检出肺气肿 97 例,检出率为 8.26%,其中男 71 例,检出率 9.90%,女 26 例,检出率 5.68%。多因素 Logistic 回归分析结果表明,吸烟、二手烟暴露及慢性支气管炎病史为肺气肿发生的主要危险因素。 结论 吸烟、二手烟暴露及慢性支气管炎病史为肺气肿发生的主要危险因素。对重点人群采取有效检测及干预措施,可以降低肺气肿的发病率及危害程度

References

[1]  1. 中华医学会呼吸病学分会慢性阻塞性肺疾病学组. 慢性阻塞性肺疾病诊治指南 (2013 年修订版)(一). 中华结核和呼吸杂志, 2013, 36(4): 484-491.
[2]  2. Yahaba M, Kawata N, Iesato K, et al. The effects of emphysema on airway disease: Correlations between multi-detector CT and pulmonary function tests in smokers. Eur J Radiol, 2014, 83(6): 1022-1028.
[3]  3. Wang R, Sui X, Schoepf UJ, et al. Ultralow-radiation-dose chest CT: accuracy for lung densitometry and emphysema detection. Am J Roentgenol, 2015, 204(4): 743-749.
[4]  4. Madani A, Zanen J, De MV, et al. Pulmonary emphysema: objective quantification at multi-detector row CT--comparison with macroscopic and microscopic morphometry. Radiology, 2006, 238(3): 1036-1043.
[5]  5. Gu S, Leader J, Zheng B, et al. Direct assessment of lung function in COPD using CT densitometric measures. Physiol Meas, 2014, 35(5): 833-845.
[6]  6. Gierada DS, Pilgram TK, Whiting BR, et al. Comparison of standard- and low-radiation-dose CT for quantification of emphysema. Am J Roentgenol, 2007, 188(1): 42-47.
[7]  7. Madani A, De Maertelaer V, Zanen J, et al. Pulmonary emphysema: radiation dose and section thickness at multi-detector CT quantification comparison with macroscopic and microscopic morphometry. Radiology, 2007, 243(1): 250-257.
[8]  8. Grydeland TB, Dirksen A, Coxson HO. Quantitative computed tomography: emphysema and airway wall thickness by sex, age and smoking. Eur Respir J, 2009, 34(4): 858-865.
[9]  9. Shaker SB, Dirksen A, Lo P, et al. Factors influencing the decline in lung density in a Danish lung cancer screening cohort. Eur Respir J, 2012, 40(5): 1142-1148.
[10]  10. Young W, Karp S, Bialick P, et al. Health, secondhand smoke exposure, and smoking behavior impacts of no-smoking policies in public housing, Colorado, 2014-2015. Prev Chronic Dis, 2016, 13: E148. Available at: https://www.cdc.gov/pcd/issues/2016/16_0008.htm.
[11]  11. 赵晶, 潘纪戍. COPD 表现型的 CT 定量诊断. 国际医学放射学杂志, 2011, 34(3): 250-256.
[12]  12. Koyama S, Sato E, Haniuda M, et al. Decreased level of vascular endothelial growth factor in bronchoalveolar lavage fluid of normal smokers and patients with pulmonary fibrosis. Am J Respir Crit Care Med, 2002, 166(3): 382-385.
[13]  13. Kasahara Y, Tuder RM, Cool CD, et al. Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor 2 in emphysema. Am J Respir Crit Care Med, 2001, 163(3 Pt 1): 737-744.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133