22. Morita K, Lo Celso C, Spencer-Dene B, et al. HAN11 binds mDia1 and controls GLI1 transcriptional activity. J Dermatol Sci, 2006, 44(1):11-20.
[2]
5. Karhadkar SS, Bova GS, Abdallah N, et al. Hedgehog signalling in prostate regeneration, neoplasia and metastasis. Nature, 2004, 431(7009):707-712.
[3]
6. Ohta M, Tateishi K, Kanai F, et al. p53-Independent negative regulation of p21/cyclin-dependent kinase-interacting protein 1 by the sonic hedgehog-glioma-associated oncogene 1 pathway in gastric carcinoma cells. Cancer Res, 65(23):10822-10829.
[4]
7. Kubo M, Nakamura M, Tasaki A, et al. Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer. Cancer Res, 64(17):6071-6074.
[5]
8. Atkinson PJ, Dellovade T, Albers D, et al. Sonic Hedgehog signaling in astrocytes is dependent on p38 mitogen-activated protein kinase and G-protein receptor kinase 2. J Neurochem. 2009, 108(6):1539-1549.
[6]
11. Engesser-Cesar C, Anderson AJ, Basso DM, et al. Voluntary wheel running improves recovery from a moderate spinal cord injury. Neurotrauma, 2005, 22(1):157-171.
[7]
17. Mao L, Xia YP, Zhou YN, et al. Activation of sonic hedgehog signaling pathway in olfactory neuroblastoma. Oncology, 2009, 77(3-4):231-243.
19. Buttitta L, Mo R, Hui CC, et al. Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. Development, 2003, 130(25):6233-6243.
2. Fuccillo M, Joyner AL, Fishell G. Morphogen to mitogen:the multiple roles of hedgehog signalling in vertebrate neural development. Nat Rev Neurosci, 2006, 7(10):772-783.
[12]
3. Watkins DN, Berman DM, Burkgolder SG, et al. Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature, 2003, 422(6929):313-317.
[13]
4. Thayer SP, di Magliano MP, Heiser PW, et al. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature, 2003, 425(6960):851-856.
[14]
9. Dai RL, Zhu SY, Xia YP, et al. Sonic hedgehog protects cortical neurons against oxidative stress. Neurochem Res, 2011, 36(1):67-75.
12. Cajal SRY. Cajal's degeneration and regeneration of the nervous system. London:Oxford University Press, 1928:105.
[17]
13. Johansson CB, Svensson M, Wallstedt L, et al. Neural stem cells in the adult human brain. Exp Cell Res, 1999, 253(2):733-736.
[18]
14. Shin SH, Kogerman P, Lindstr？m E, et al. GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization. Proc Natl Acad Sci U S A, 1999, 96(6):2880-2884.
[19]
15. Lipinski RJ, Gipp JJ, Zhang J, et al. Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling. Exp Cell Res, 2006, 312(11):1925-1938.
[20]
16. Sims JR, Lee SW, Topalkara K, et al. Sonic hedgehog regulates ischemia/hypoxia-induced neural progenitor proliferation. Stroke, 2009, 40(11):3618-3626.
[21]
20. Eichberger T, Sander V, Schnidar H, et al. Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes. Genomics, 2006, 87(5):616-632.
[22]
21. Lai K, Kaspar BK, Gage FH, et al. Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat Neurosci, 2003, 6(1):21-27.
[23]
23. Nolan-Stevaux O, Lau J, Truitt ML, et al. GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes Dev, 2009, 23(1):24-36.
