将类丁二炔(10, 12-二十五碳二炔酸)囊泡固载于琼脂糖凝胶制备出了新型辐射变色凝胶复合凝胶材料。利用γ射线辐照研究了所制备凝胶的辐照响应行为,结果显示:当γ辐射剂量在500-2000 Gy内,随着剂量增加,凝胶由无色逐渐变为蓝色,颜色不断加深,采用紫外-可见光分光光度计测试其吸收光谱,发现其主要吸收峰值在660 nm附近,且辐照前后凝胶的吸光度差值与剂量有良好线性关系(相关系数R2 =0.9942)。进一步研究表明:所制备的凝胶材料对γ射线和电子束辐照有相同的剂量响应,且无明显的能量和剂量率依赖性;凝胶的辐射后效应较弱,辐照后24 h,吸光度基本恒定;分次辐照对凝胶剂量计准确性的影响极小;凝胶在0-30℃范围内的响应性基本保持稳定;在辐照后48 h内,并未观察到囊泡有明显扩散效应,显示出良好的稳定性。此外,琼脂糖具有价廉、无毒且易制备为任意形状凝胶的优点,因此该凝胶剂量计有望应用于真实场景的三维剂量分布测定。 A new diacetylene/agarose gel dosimeter composed of agarose gel as the carrier and diacetylene (10, 12-pentacosadiynoic acid) vesicles as the radiochromic agent was prepared and its response behavior to γ-radiation was studied. Ultraviolet-visible spectra showed that the main absorption peak was around 660 nm, and there was a distinct linear relationship (correlation coefficient R2 = 0.9942) between the absorbed dose and absorbance at 660 nm over the absorbed dose range from 500 to 2000 Gy. The diacetylene/agarose gel dosimeter exhibited the same dose response to γ-radiation and an electron beam without energy and dose rate dependency. Furthermore, the effects of temperature, diffusion, fractionated irradiation, and post-radiation on the dosimeter response were carefully investigated. The developed diacetylene/agarose gel dosimeter shows promise to measure the three-dimensional space dose within the range of 500-2000 Gy
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