16周有氧运动对社区高血压患者焦虑水平以及相关激素的影响
Effects of 16 Weeks Aerobic Exercise on Anxiety Level and Related Hormones of Hypertension Patients in Community

摘要：研究目的:探讨中等强度有氧运动对原发性高血压患者血压、焦虑状况的影响及相关机制。研究方法:筛选社区高血压病患者20人（男3名、女17名），平均年龄为62.50±2.82岁；施以1h/天、6天/周中等强度运动；在运动16周前中后分别填写心理焦虑量表，检测身高、体重、腰围、血压、体脂百分比以及血管紧张素Ⅱ、肾上腺素、皮质醇。研究结果:1）与运动前相比，16周运动后维持抗压药正常量的人数从90%下降至45%，35%受试者服药量减半，不服药的人数增长了10%；2）运动16周末受试者SBP、DBP均出现非常显著性的降低（p＜0.01），且脉压差也有显著性的降低（p＜0.05）；3）运动16周后焦虑水平有显著性的下降（p＜0.01），且近69%高血压患者的焦虑状况得到明显的改善；4）运动16周后血清AngⅡ、E以及COR的含量均有非常显著性降低（p＜0.01）。研究结论:1）中等强度运动能有效降低高血压患者的血压；2）中等强度运动能明显改善高血压患者的焦虑水平，且情绪向良性发展；3）中等强度运动能够显著降低高血压患者血清AngⅡ、E以及COR的含量，这可能是中等强度运动有效改善高血压患者焦虑状况及降低血压的生理生化基础。
Abstract: Objective: To study the effect of the moderate-intensity aerobic exercise on blood pressure (BP), anxiety of hypertension patients and the related mechanism. Methods: Twenty hypertension patients (3 males and 17 females) in community were recruited in this study, their average age was 62.50±2.82 yrs, and they participated in a 16 weeks moderate-intensity aerobic exercise program (1 hour/day, 6 days/ week). Patients practiced a moderate-intensity aerobic training program (1 hour per time,6 times per week). Psychological anxiety scale, height, body weight, waist circumference, blood pressure, percentage of body fat, AngⅡ,E and COR were measured in all patients before training and at the end of eighth week and after 16 weeks training. Results: 1) Compared with pre training, the number of patients taking normal does of hypotensor reduced from 90% to 45% after 16 weeks training, 35% of the subjects only took half dose, and the number of patients not taking medicine increased by 10%; 2) After 16 weeks training, both SBP and DBP of patients decreased significantly (P < 0.01), and the pulse pressure also decreased obviously (P < 0.05). 3) After 16 weeks training, patient’s anxiety level decreased (P < 0.01), and about 69% patients was getting better. 4) After 16 weeks training, the content of Ang II, E and COR in serum decreased (P < 0.01). Conclusions: 1) Moderate-intensity exercise can effectively reduce hypertensive patients’ blood pressure. 2) Moderate-intensity exercise can significantly alleviate hypertension patients’ anxiety level and promote a healthy emotional development. 3) Moderate-intensity exercise can significantly reduce hypertensive patients’ serum Ang II, E and content of COR, which may be the biochemical basis of moderate-intensity exercise effectively alleviating anxiety and reducing blood pressure in hypertensive patients