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- 2018
重庆部分地区牛弓形虫血清流行病学调查及危险性因素分析
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Abstract:
采用分析流行病学的“病例-对照研究”和弓形虫抗体ELISA检测方法，对重庆市牛弓形虫血清流行病学进行调查和危险性因素分析.从10个区县所采集的345份牛血清样本中，共检出弓形虫抗体阳性血清94份，平均阳性率为27.25%(94/345)，其中公牛和母牛弓形虫感染的阳性率分别为19.25%(36/187)，36.71% (58/158)；1岁以上的成年牛和小于1岁幼年牛弓形虫的阳性感染率分别为31.06%(82/264)，14.81%(12/81)；无犬猫牛场弓形虫的感染率为23.40%(33/141)，有犬猫牛弓形虫的感染率为29.90%(61/204).危险性因素分析显示，成年牛弓形虫感染率是幼年牛的2.59倍(OR=2.59，X2=8.25，95% CI=1.33~1.5.04，p=0.004)，表明重庆地区年龄因素对牛弓形虫病流行有中等程度的关联；母牛弓形虫感染率是公牛感染率的2.43倍(OR=2.43，X2=13.17，95% CI=1.50~3.96，p=0)，表明重庆地区性别因素对牛弓形虫病流行有中等程度的关联；有犬猫牛弓形虫的感染率是无犬猫的1.40倍(OR=1.40，X2=1.77，95% CI=0.85~2.28，p=0.183)，表明重庆地区有无犬猫对牛弓形虫病流行有较弱的关联.
The objective of this work was to test sero-prevalence of Toxoplasma gondii from cattle in Chongqing. A total of 345 serum samples were obtained from 10 districts/counties of the city and tested for T. gondii antibody by ELISA, of which 94 were found to be positive for T. gondii antibody, the average positive rate being 27.25% (94/345). The positive rates of T. gondii infection in bulls and cows were 19.25% (36/187) and 36.71% (58/158), respectively. The positive rates of T. gondii infection in adult cattle (≥1-year-old) and calves (< 1-year-old) were 31.06% (82/264) and 14.81% (12/81), respectively. On cattle farms with dogs or cats, the infection rate was 29.90% (61/204), being higher than that on farms without dogs or cats 23.40% (33/141). Based on risk factor analysis, T. gondii sero-prevalence was found to be in moderate association with the age (OR=2.59, X2=8.25, 95% CI=1.33-1.5.04)and the gender of the cattle (OR=2.43, X2=13.17, 95% CI=1.50-3.96), and in weak association with the presence of cats or dogs (OR=1.40, X2=1.77, 95% CI=0.85-2.28, p=0.183)
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