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- 2018
猪圆环病毒Ⅱ型吉林株对小鼠的致病力研究
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Abstract:
选取磐石病毒株(PS0901)、蛟河病毒株(JH0901)、桦甸病毒株(HD0901)、舒兰病毒株(SL0901)为试验材料,对猪圆环病毒Ⅱ型吉林株的致病力展开试验研究.结果显示,蛟河病毒株(JH0901)、桦甸病毒株(HD0901)对于小鼠脾脏和肾脏的致病力都比较明显.
The virus strain of Panshi (PS0901), Jiaohe (JH0901), Huadian (HD0901) and Shulan (SL0901) were selected as experimental materials to study the pathogenicity of porcine circovirus type Ⅱ strain Jilin. The results showed that the virus strain of Jiaohe (JH0901) and Huadian (HD0901) had obvious pathogenicity to spleen and kidney of mice
[1] | FENAUX M, OPRIESSNIG T, HALBUR P G, et al. Two Amino Acid Mutations in the Capsid Protein of Type 2 Porcine Circovirus (PCV2) Enhanced PCV2 Replication In Vitro and Attenuated the Virus In Vivo[J]. Jounal of Virology, 2014, 13(4): 440-446. |
[2] | CHEUNG A K. Comparative Analysis of the Transcriptional Patterns of Pathogenic and Nonpathogenic Porcine Circoviruses[J]. Virol, 2013, 310(1): 41-49. |
[3] | ALLAN G M, ELLIS J A. Porcine Circoviruses:a Review[J]. Vet Diagn Invest, 2015, 12(4): 3-14. |
[4] | SHAN Y, SUSAN C, TANJA O, et al. Development of a Reverse Transcription-PCR Assay to Detect Porcine Circovirus Type 2 Transcription as a Measure of Replication[J]. Journal of Virological Methods, 2015, 123(1): 109-112. |
[5] | LIPEJ Z, SEGALES J, JEMERSIC L, et al. First Description of Postweaning Multisystemic Wasting Syndrome (PMWS) in Wild Boar (Susscrofa) in Croatia and Phylogenetic Analysis of Partial PCV2 Sequences[J]. Acta Vet Hung, 2017, 55(3): 389-404. |
[6] | 刘长明, 危艳武, 陆月华, 等. 猪圆环病毒2型灭活疫苗(LG株)的研制与应用[J]. 畜牧兽医科学信息, 2015, 29(9): 29-30. |
[7] | TUIJA KEKARAINEN T M, MONTOYA M, MATEU E, et al. Porcine Circovirus Type 2-Induced Interleukin-10 Modulates Recall Antigen Responses[J]. Journal of General Virology, 2015, 89(11): 760-765. |
[8] | TIMMUSK S, FOSSUM C, BERG M. Porcine Circovirus Type 2 Replicase Binds the Capsid Protein and an Intermediate Filament-Like Protein[J]. Gen. Virol, 2016, 87(11): 315-323. |
[9] | 罗玉均, 张桂红, 陈建红, 等. 圆环病毒2型对BALB/c小鼠的感染试验研究[J]. 黑龙江畜牧兽医, 2008(10): 55-57. DOI:10.3969/j.issn.1004-7034.2008.10.029 |
[10] | RUIZ F F, VICENTE J, VIDAL D, et al. Seroprevalence of Six Reproductive Pathogens in European Wild Boar(Susscrofa) from Spain:the Effect on Wild Boar Female Reproductive Performance[J]. Theriogenology, 2016, 65(4): 731-743. |
[11] | 刘艳芳. 运用Markov链对我国猪肉产量进行趋势预测[J]. 中国猪业, 2012, 10(3): 7-10. |
[12] | MAGAR R, MULLER P, LAROCHELLE R. Retrospective Serological Survey of Antibodiesto Porcine Circovirus Type 1 and Type 2[J]. Can Vet Res, 2015, 64(8): 184-186. |
[13] | 崔尚金, 蔡阳, 陈欣. 检测猪圆环病毒DNA的竞争定量PCR方法的建立及初步应用[J]. 中国预防兽医学报, 2004, 26(5): 347-352. DOI:10.3969/j.issn.1008-0589.2004.05.008 |
[14] | 苗岚飞, 崔尚金, 张超范, 等. 猪圆环病毒2型感染昆明小鼠模型的建立[J]. 中国兽医科学, 2008, 38(6): 475-478. |
[15] | OPRIESSNIG T, RAMAMOORTHY S, MADSON D M, et al. Differences in Virulence among Porcine Circovirus Type 2 Isolates are Unrelated to Cluster Type 2a or 2b and Prior Infection Provides Heterologous Protection[J]. Journal of General Virology, 2016, 89(5): 2482-2491. |