|
|
- 2018
牙龈卟啉单胞菌fimA分型与相关疾病的研究
|
Abstract:
摘要 牙龈卟啉单胞菌与牙周组织感染、糖尿病、冠状动脉粥样硬化性心脏病(简称冠心病)等疾病的发生发展密切相关。菌毛是牙龈卟啉单胞菌重要的毒力因子,可以协助牙龈卟啉单胞菌黏附和入侵宿主细胞。根据FimA蛋白编码基因fimA核苷酸序列的不同可将其分为Ⅰ、Ⅰb、Ⅱ、Ⅲ、Ⅳ和Ⅴ等6种基因型,不同fimA基因型菌株的致病力和与疾病的相关性有一定差异。本文重点综述近年来不同fimA基因型牙龈卟啉单胞菌菌毛与相关疾病的研究进展
| [1] | Hasegawa Y, Nagano K, Ikai R, et al. Localization and function of the accessory protein Mfa3 in Porphyromonas gingivalis Mfa1 fimbriae [J]. Mol Oral Microbiol, 2013, 28(6)∶467-480 |
| [2] | Feng X, Zhang L, Xu L, et al. Detection of eight periodontal microorganisms and distribution of Porphyromonas gingivalis fimA genotypes in Chinese patients with aggressive periodontitis [J]. J Periodontol, 2014, 85(1)∶150-159 |
| [3] | Perez-Chaparro PJ , Rouillon A , Minet J , et al. fimA genotypes and PFGE profile patterns in Porphyromonas gingivalis isolates from subjects with periodontitis [J]. Oral Microbiol Immunol, 2010, 24(5)∶423-426 |
| [4] | 李彦君,潘亚萍,陈旭,等.不同fimA基因型牙龈卟啉单胞菌在青春期龈炎患者中的分布[J].口腔医学研究,2012,28(6)∶556-559 |
| [5] | Miura M, Hamachi T, Fujise O, et al. The prevalence and pathogenic differences of Porphyromonas gingivalis fimA genotypes in patients with aggressive periodontitis [J]. J Periodontal Res, 2005, 40(2)∶147-152 |
| [6] | Fabrizi S, Len R, Blanc V, et al. Variability of the fimA gene in Porphyromonas gingivalis isolated from periodontitis and non-periodontitis patients [J]. Med Oral Patol Oral Cir Bucal, 2013, 18(1)∶e100 |
| [7] | Leishman SJ, Do HL, Ford P. Cardiovascular disease and the role of oral bacteria [J]. J Oral Microbio, 2010, 2(1)∶5781 |
| [8] | Hasegawa Y, Murakami Y. Porphyromonas gingivalis fimbriae: Recent developments describing the function and localization of mfa1 gene cluster proteins [J]. J Oral Biosci, 2014, 56(3)∶86-90 |
| [9] | Kristoffersen AK, Solli SJ, Nguyen TD, et al. Association of the rgpB gingipain genotype to the major fimbriae (fimA) genotype in clinical isolates of the periodontal pathogen Porphyromonas gingivalis [J]. J Oral Microbio, 2015, 7∶29124 |
| [10] | 杨炳涛,徐菁玲,和璐,等.伴糖尿病牙周炎患者牙龈卟啉单胞菌 FimA 基因型的检测[J].中华口腔医学杂志,2016,51(1)∶20-24 |
| [11] | Pan S, Liu Y, Si Y, et al. Prevalence of fimA genotypes of Porphyromonas gingivalis in adolescent orthodontic patients [J]. PLoS One, 2017, 12(11)∶e0188420 |
| [12] | Krishnan M, Krishnan P, Chandrasekaran SC. Detection of Porphyromonas gingivalis fimA type Ⅰ genotype in gingivitis by Real-time PCR-a pilot study [J]. J Clin Diagn Res, 2016, 10(6)∶ZC32-ZC35 |
| [13] | Ras IN, Siqueira JF. Distribution of Porphyromonas gingivalis fimA genotypes in primary endodontic infections [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2010, 109(3)∶474-478 |
| [14] | 唐路,薛栋,白雨豪,等.颈动脉粥样硬化斑块中牙龈卟啉单胞菌菌毛fimA基因型的分布研究[J].现代口腔医学杂志, 2017,31(6)∶321-325 |
| [15] | Amano A. Bacterial adhesins to host components in periodontitis [J]. Periodontol 2000, 2010, 52(1)∶12-37 |
| [16] | Hayashi F, Okada M, Oda Y, et al. Prevalence of Porphyromonas gingivalis fimA genotypes in Japanese children [J]. J Oral Sci, 2012, 54(1)∶77-83 |
| [17] | 唐路,曹日丹,曾红燕.牙龈卟啉单胞菌菌毛fimA基因型在牙周牙髓联合病变中的分布[J].北京口腔医学, 2015, 23(6)∶321-324 |
| [18] | Pathirana RD, O'Brien-Simpson NM, Reynolds EC. Host immune responses to Porphyromonas gingivalis, antigens [J]. Periodontol 2000, 2010, 52(1)∶218-237 |
| [19] | Wang Q, Zhou X, Zheng Q, et al. Distribution of Porphyromonas gingivalis fimA genotypes in chronic apical periodontitis associated with symptoms [J]. J Endod, 2010, 36(11)∶1790-1795 |
| [20] | Ziver T, Balci A, Ergin S, et al. The role of Porphyromonas gingivalis in the development of atherosclerosis and its relationship with fimA genotype [J]. Clin Lab, 2014, 11(12)∶1 |
| [21] | Nakano K, Inaba H, Nomura R, et al. Distribution of Porphyromonas gingivalis fimA genotypes in cardiovascular specimens from Japanese patients [J]. Oral Microbiol Immunol, 2008, 23(2)∶170-172 |
| [22] | Ziver T, Balci A, Ergin S, et al. The role of Porphyromonas gingivalis in the development of atherosclerosis and its relationship with fim A genotype [J]. Clin Lab, 2014, 60(7)∶1225-1232 |
