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- 2016
下颌前伸式阻鼾器的改良及对轻中度OSA的临床疗效评价
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Abstract:
摘要 目的: 对临床常用的胶联一体下颌前伸式阻鼾器进行改良,评价其对轻、中度阻塞型睡眠呼吸暂停综合征(OSA)的临床疗效。方法: 40例经多导睡眠呼吸监测(PSG)确诊为轻、中度OSA(5＜AHI＜30)的患者,随机将其均分为实验组及对照组,分别佩戴改良一体式阻鼾器和软压膜一体式阻鼾器,佩戴前及3月后行个人问卷调查及PSG监测,分别记录患者主观症状及睡眠参数变化,比较两组治疗前、后情况差异。结果: 与治疗前比较, 实验组18例的AHI下降了50%以上,客观有效率为90%,高于对照组55%;实验组治疗后N1%显著减少、N2%和N3%显著增加(P<0.05),对照组治疗前、后睡眠结构没有明显改善。实验组主观症状改善率高于对照组,无睡眠中阻鼾器脱落现象发生。结论: 改良一体式阻鼾器对于轻、中度OSA有更好的治疗效果,在OSA的治疗中有广阔的临床应用价值
| [1] | Helen Gotsopoulos, Carol Chen, Jin Qian, et al. Oral Appliance Therapy Improves Symptoms in Obstructive Sleep Apnea [J]. American Journal of Respiratory and Critical Care Medicine, 2002, 166(5)∶743-748 |
| [2] | 孙晓强,易红良,张玉君,等.UPPP联合GAHM术后OSAHS患者睡眠结构的变化[J].上海交通大学学报(医学版), 2007, 9(27)∶1071-1074 |
| [3] | Al-Rafah EM, Alammari MR, Banasr FH. The Efficacy of Bilateral Balanced and Canine Guidance Occlusal Splints in the Treatment of Temporomandibular Joint Disorder [J]. OHDM , 2014, 13(2)∶536-42 |
| [4] | Bonham PE, Currier GF, Orr WC, et al. The effect ofmodified functional appliance on obstructive sleep apnea [J]. Am JO rthod DentofacO rthop, 1988, 94(2)∶384-388 |
| [5] | LoweAA, Sj holm TT, Ryan CF, et al. Treatment, airway and compliance effects of a titratable oral appliance [J]. Sleep, 2000, 23(4)∶S172 |
| [6] | 中华医学会呼吸病学分会睡眠呼吸障碍学组.阻塞性睡眠呼吸暂停低通气综合征诊治指南(2011年修订版)[J].中华结核和呼吸杂志,2012,35(1)∶9-12 |
| [7] | 余哲,赵颖.OSAHS患者戴用下颌前移矫治器后咀嚼肌肌电活性变化的研究[J].口腔医学研究,2015, 31(3)∶276-279 |
| [8] | LS Bennett, RJ Davies and JR Stradling.Oral appliances for the management of snoring and obstructive sleep apnoe [J]. Thorax, 1998, 53(1)∶58-64 |
| [9] | Kushida CA, Morgenthaler TI, Littner MR, et al. Practice parameters for the treatment of snoring and sleep apnea with oral appliances: an update [J]. Sleep, 2006, 29(2)∶240-243 |
| [10] | 徐超,谢宇平,康宏,等.中重度阻塞性睡眠呼吸暂停综合征患者腭咽成形术后佩戴改良一体式阻鼾器的疗效[J].中华医学杂志, 2015, 10(96)∶761-765 |
| [11] | 惠培林,谢宇平,魏晓泉,等.阻鼾器与鼻腔和口咽联合手术治疗重度OSAHS的临床效果观察[J].临床耳鼻咽喉头颈外科杂志,2015, 6(4)∶504-508 |
| [12] | 弓煦,赵颖,高雪梅,等.阻塞性睡眠呼吸暂停低通气综合征患者戴用口腔矫治器6年以上牙改变[J].北京大学学报(医学版),2011,2(43)∶280- 284 |
| [13] | YoungT, Skatrud J, Peppard PE. Risk factors for obstructive sleep apnea in adults [J]. JAMA, 2004, 291(16)∶2013-2016 |
