|
|
- 2018
Ti6AL4V表面微弧氧化法制备含锌涂层的特征及抗菌性研究
|
Abstract:
摘要 目的: 微弧氧化法在Ti6AL4V上制备不同浓度含锌涂层,比较其表面特征及抗菌性。方法: 用微弧氧化法在Ti6AL4V表面制备不同浓度含锌涂层的4组试件,即无锌组(N-Zn),低锌组(L-Zn),中锌组(M-Zn),高锌组(H-Zn),以抛光后Ti6AL4V(CP)作为对照组;扫描电镜及能谱仪观察涂层表面形貌、元素原子比例;X线衍射仪测定物相组成;贴膜法测定试件对大肠杆菌和金黄色葡萄球菌的抑制效果。结果: 1)扫描电镜观察,随着锌浓度增高,涂层表面孔径变小,变均匀,但在H-Zn组表面出现涂层断裂情况;2)能谱仪显示,与CP组相比,四组实验组表面均出现了Ca、P等元素,测得Ca/P的比值为1.7;3)X线衍射仪结果表明实验组表面均形成了锐钛矿相、金红石相;4)贴膜实验表明,与CP组相比,实验组菌落均具有统计学差异(P＜0.05);M-Zn组与H-Zn组相比,菌落数无统计学差异(P＞0.05)。结论: 微弧氧化法制备的含锌涂层可以增强试件表面抗菌性能,抗菌性能随涂层含锌浓度升高而增强
| [1] | Zong M, Bai L, Liu Y, et al. Antibacterial ability and angiogenic activity of Cu-Ti-O nanotube arrays [J]. Mater Sci Eng C Mater Biol Appl,2017,71∶93-99 |
| [2] | 贺丹枫.医用Ti6Al4V合金表面HA及DLC/HA涂层的制备及表征[D].中国矿业大学,2017 |
| [3] | 孙千月,梁丹,郭天奇,等.纳米锌抗菌机理的研究进展[J].口腔医学研究,2015,31(2)∶195-197 |
| [4] | Rokosz K, Hryniewicz T, Mat sek D, et al. SEM,EDS and XPS analysis of the coatings obtained on Titanium after plasma electrolytic oxidation in electrolytes containing copper nitrate [J]. Materials (Basel), 2016, 9(5). pii∶E318 |
| [5] | Mishra SK, Chowdhary R, Kumari S. Microleakage at the different implant abutment interface: a systematic review [J]. J Clin Diagn Res,2017,11(6)∶ZE10 |
| [6] | 王方辉,张姗姗,舒静媛,等.纯钛种植体表面改性对骨结合的影响[J].中国组织工程研究,2014,18(52)∶8491-8497 |
| [7] | Ran W, Tian ZH, Guo B, et al.Superior biocompatibility and osteogenic efficacy of micro-arc oxidation-treatedtitanium implants in the canine mandible [J]. Biomed Mater, 2009,4(5)∶055003 |
| [8] | Krz ka a A, Kazekk sik A, Simka W. Application of plasma electrolytic oxidationto bioactive surface formationon titanium and its alloys [J]. Rsc Advances,2013,3(43)∶19725-19743 |
| [9] | 陆雨桐,李涛,商晓盼,等.不同电压对镁合金微弧氧化膜理化性能及生物活性的影响[J].中国医学物理学杂志,2017,34(5)∶502-508 |
| [10] | Wang W, Peng W, Chen L, et al. Degradation and biological properties of Ca-P contained micro-arc oxidation self-sealing coating on pure magnesium for bone fixation [J]. Regen Biomater,2015,2(2)∶107-118 |
| [11] | Huang Y, Zhang X, Mao H, et al. Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method [J]. Rsc Advances, 2015, 5(22)∶17076-17086 |
| [12] | Hu H, Zhang W, Qiao Y, et al. Antibacterial activity and increased bone marrow stem cell functions of Zn-incorporated TiO<sub>2</sub> coatings on titanium [J]. Acta Biomaterialia,2012,8(2)∶904-915 |
| [13] | Degidi M, Artese L, Piattelli A, et al. Histological and immunohistochemical evaluation of the peri-implant soft tissues around machined and acid-etched titanium healing abutments:aprospective randomised study [J]. Clin Oral Investig, 2012,16(3)∶857-866 |
| [14] | Xu J, Ding G, Li J, et al. Zinc-ion implanted and deposited titanium surfaces reduce adhesion of Streptococccusmutans [J]. Applied Surface Science,2010,256(24)∶7540-7544 |
| [15] | Yao X, Zhang X, Wu H, et al. Microstructure and antibacterial properties of Cu-doped TiO<sub>2</sub>,coating on titanium bymicro-arc oxidation [J]. Applied Surface Science,2014,292(1)∶944-947 |
| [16] | 丁明超,李德超.种植体表面制备载银涂层的方法[J].中国口腔种植学杂志,2011,16(2)∶139-143 |
| [17] | Raghupathi KR, Koodali RT, Manna AC. Size-dependent bacterial growth inhibition and mechanism of antibacterial activity of zinc oxide nanoparticles [J]. Langmuir, 2011, 27(7)∶4020-4028 |
