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- 2018
牙髓干细胞在牙髓牙本质再生中的研究进展
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Abstract:
摘要 近年来,以牙髓干细胞作为种子细胞实现牙髓牙本质再生的研究受到国内外学者的广泛关注。学者们应用组织工程技术,从支架材料、生长因子以及共同的微环境等多方面进行探索,试图寻找到更理想的方法将牙髓干细胞应用于牙髓牙本质再生。本文将概述牙髓干细胞在牙髓牙本质再生中的研究进展
| [1] | Iohara K, Zheng L, Ito M, et al. Regeneration of dental pulp after pulpotomy by trans-plantation of CD31(-)/CD146(-) side population cells from a canine tooth [J] . Regen Med, 2009, 4(3)∶377-385 |
| [2] | Ishizaka R,Hayashi Y,Iohara K,et al. Stimulation of angiogenesis, neurogenesis and regeneration by side population cells from dental pulp [J] . Biomaterials,2013,34(8)∶1888-1897 |
| [3] | Dissanayaka WL, Hargreaves KM, Jin L, et al. The interplay of dental pulp stem cells and endothelial cells in an injectable peptide hydrogel on angiogenesis and pulp regeneration <em>in vivo</em> [J] . Tissue Eng Part A, 2015, 21(3-4)∶550-563 |
| [4] | Ferroni L, Gardin C, Sivolella S, et al. A hyaluronan-based scaffold for the <em>in vitro</em> construction of dental pulp-like tissue [J] . Int J Mol Sci, 2015, 16(3)∶4666-4681 |
| [5] | Hilkens P, Bronckaers A, Ratajczak J, et al. The angiogenic potential of DPSCs and SCAPs in an <em>in vivo</em> model of dental pulp regeneration [J] . Stem Cells Int, 2017, 2017∶2582080 |
| [6] | Liu G, Xu G, Gao Z, et al. Demineralized dentin matrix induces odontoblastic differentiation of dental pulp stem cells[J] . Cells Tissues Organs, 2016, 201(1)∶65-76 |
| [7] | Iohara K, Zheng L, Wake H, et al. A novel stem cell source for vasculogenesis in ischemia: subfraction of side population cells from dental pulp [J] . Stem Cells, 2008, 26(9)∶2408-2418 |
| [8] | Hu L, Gao Z, Xu J, et al. Decellularized swine dental pulp as a bioscaffold for pulp regeneration [J] . Biomed Res Int, 2017, 2017∶9342714 |
| [9] | Galler KM,Brandl FP,Kirchhof S,et al. Suitability of different natural and synthetic biomaterials for dental pulp tissue engineering [J] . Tissue Eng Part A,2018,24(3-4)∶234-244 |
| [10] | Suzuki T, Lee CH, Chen M, et al. Induced migration of dental pulp stem cells for <em>in vivo</em> pulp regeneration [J] . Dent Res, 2011, 90(8)∶1013-1018 |
| [11] | Teti G, Salvatore V, Focaroli S, et al. <em>In vitro</em> osteogenic and odontogenic differentiation of human dental pulp stem cells seeded on carboxymethyl cellulose-hydroxyapatite hybrid hydrogel [J] . Front Physiol, 2015, 6∶297 |
| [12] | Sakai VT, Zhang Z, Dong Z, et al. SHED differentiate into functional odontoblasts and endothelium [J] . J Dent Res, 2010, 89(8)∶791-796 |
| [13] | Zou T, Dissanayaka WL, Jiang S, et al. Semaphorin 4D enhances angiogenic potential and suppresses osteo-/odontogenic differentiation of human dental pulp stem cells [J] . J Endod, 2017, 43(2)∶297-305 |
| [14] | Qu T, Liu X. Nano-structured gelatin/bioactive glass hybrid scaffolds for the enhancement of odontogenic differentiation of human dental pulp stem cells [J] . J Mater Chem B, 2013, 1(37)∶4764-4772 |
| [15] | Zheng L, Yang F, Shen H, et al. The effect of composition of calcium phosphate composite scaffolds on the formation of tooth tissue from human dental pulp stem cells [J] . Biomaterials, 2011, 32(29)∶7053-7059 |
| [16] | Zhu L, Ma J, Mu R, et al. Bone morphogenetic protein 7 promotes odontogenic differentiation of dental pulp stem cells <em>in vitro</em> [J] . Life Sci, 2018, 202∶175-181 |
| [17] | Zhang W,Liu W,Ling J,et al. Odontogenic differentiation of vascular endothelial growth factor-transfected human dental pulp stem cells <em>in vitro</em>. Mol Med Rep,2014,10(4)∶1899-906 |
| [18] | Zhu Q, Gao J, Tian G, et al. Adrenomedullin promotes the odontogenic differentiation of dental pulp stem cells through CREB/BMP2 signaling pathway [J] .Acta Biochim Biophys Sin (Shanghai), 2017, 49(7):609-616 |
| [19] | Liu M,Zhao L,Hu J,et al. Endothelial cells and endothelin-1 promote the odontogenic differentiation of dental pulp stem cells [J] . Mol Med Rep, 2018, 18(1): 893-901 |
| [20] | Heng BC, Ye X, Liu Y, et al. Effects of recombinant overexpression of Bcl2 on the proliferation, apoptosis, and osteogenic/odontogenic differentiation potential of dental pulp stem cells [J] . J Endod, 2016, 42(4)∶575-583 |
| [21] | Cui L, Xu S, Ma D, et al. The role of integrin-α5 in the proliferation and odontogenic differentiation of human dental pulp stem cells [J] . J Endod, 2014, 40(2)∶235-240 |
| [22] | He L, Pan S, Li Y, et al. Increased proliferation and adhesion properties of human dental pulp stem cells in PLGA scaffolds via simulated microgravity [J] . Int Endod J, 2016, 49(2)∶161-173 |
| [23] | Gronthos S, Mankani M, Brahim J, et al. Postnatal human dental pulp stem cells(DPSCs) <em>in vitro</em> and vivo [J] . Proc Natl Acad Sci U S A, 2000, 97(25)∶13625-13630 |
| [24] | Atalayin C, Tezel H, Dagci T, et al. <em>In vivo</em> performance of different scaffolds for dental pulp stem cells induced for odontogenic differentiation[J] . Braz Oral Res, 2016, 30(1)∶e120 |
| [25] | Kuang R, Zhang Z, Jin X, et al. Nanofibrous spongy microspheres enhance odontogenic differentiation of human dental pulp stem cells [J] . Adv Healthc Mater, 2015, 4(13)∶1993-2000 |
| [26] | Paduano F, Marrelli M, White LJ, et al. Odontogenic differentiation of human dental pulp stem cells on hydrogel scaffolds derived from decellularized bone extracellular matrix and collagen type I [J] . PLoS One, 2016, 11(2)∶e0148225 |
| [27] | Piva E, Silva AF, N r JE. Functionalized scaffolds to control dental pulp stem cell fate [J] . J Endod, 2014, 40(4)∶S33-S40 |
| [28] | Heng BC, Wang S, Gong T, et al. EphrinB2 signaling enhances osteogenic/odontogenic differentiation of human dental pulp stem cells [J] . Arch Oral Biol, 2018, 87∶62-71 |
| [29] | Sohn S, Park Y, Srikanth S, et al. The Role of ORAI1 in the odontogenic differentiation of human dental pulp stem cells[J] . J Dent Res, 2015, 94(11)∶1560-1567 |
| [30] | Dissanayaka WL, Zhu L, Hargreaves KM, et al. Scaffold-free prevascularized microtissue spheroids for pulp regeneration [J] . J Dent Res, 2014, 93(12)∶1296-1303 |
| [31] | Dissanayaka WL, Zhu L, Hargreaves KM, et al. <em>In vitro</em> analysis of scaffold-free prevascularized microtissue spheroids containing human dental pulp cells and endothelial cells[J] . J Endod, 2015, 41(5)∶663-670 |
| [32] | Ravindran S, Zhang Y, Huang CC, et al. Odontogenic induction of dental stem cells by extracellular matrix-inspired three-dimensional scaffold [J] . Tissue Eng Part A, 2014, 20(1-2)∶92-102 |
| [33] | Seang S,Pavasant P,Limjeerajarus CN. Iloprost induces dental pulp angiogenesis in a growth factor-free 3-dimensional organ culture system [J] . J Endod,2018,44(5)∶759-764 |
| [34] | Pan S,Dangaria S,Gopinathan G, et al. SCF promotes dental pulp progenitor migration, neovascularization, and collagen remodeling-potential application as a homing in dental pulp regeneration [J] . Stem Cell Rev, 2013, 9(5)∶655-667 |
| [35] | Mangione F, EzEldeen M, Bardet C, et al. Implanted dental pulp cells fail to induce regeneration in partial pulpotomies [J] . J Dent Res, 2017, 96(12)∶1406-1413 |
