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- 2018
修复重建后口腔癌患者生存质量的影响因素分析
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Abstract:
摘要 目的:生理、社会适应及心理因素严重影响着口腔癌患者的生存质量(Quality of Life,QOL),本研究着重调查口腔癌患者肿瘤切除术后即刻修复重建对其生存质量的影响。方法:通过华盛顿大学生存质量量表中文第四版(UWQOL)评估分别应用胸大肌肌皮瓣(PMM)及游离股前外侧皮瓣(ALT)修复重建的口腔癌术后患者,经过测评得分后对数据进行分析,探讨年龄、性别、颈淋巴结清扫术式、切除的范围、下颌骨断开与否、牙齿情况及放疗情况等因素对患者生存质量影响的程度。结果:此次调查共发放问卷98份,收回问卷85份,回收率86.7%,其中应用胸大肌肌皮瓣修复的患者40例(47%),应用游离股前外侧皮瓣修复的患者45例(53%),在胸大肌肌皮瓣修复的患者组别中,年龄、颈淋巴结清扫术式、下颌骨断开与否及放疗的应用明显影响组内患者的生存质量,而在游离股前外侧皮瓣修复的患者组别中,年龄、性别、颈淋巴结清扫术式、下颌骨断开与否、及放疗的应用则明显影响组内患者的生存质量。结论:这两组患者影响其生存质量的共同因素有年龄、颈淋巴结清扫术式、下颌骨是否断开及放疗应用,因此针对治疗的每一步骤,临床医师应充分考虑患者可能的生存质量的变化
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