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- 2017
产前诊断唇腭裂畸形的研究进展
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Abstract:
摘要 唇腭裂是胎儿颜面部最常见的先天性畸形,一半的病例为唇裂合并腭裂,可以孤立存在,也可合并与一些先天性畸形合并存在。由于唇腭裂畸形影响新生儿面容、吸吮、吞咽、语言及面部发育等功能,导致身心发育不良,给患儿和家庭带来不良影响。产前早期诊断胎儿唇腭裂畸形有利于孕妇得知胎儿患有唇腭裂畸形后向产科、儿科及正畸专家咨询及时作出是否继续妊娠的选择。产前超声检查是早期诊断唇腭裂最主要及最重要的筛选及诊断方法,并可进行唇腭裂分型并系统检查胎儿是否有其它器官合并畸形;胎儿磁共振对超声发现的唇腭裂特别是腭裂的诊断和严重程度评估上起辅助诊断作用。产前优生遗传检查可确定唇腭裂胎儿是否合并有染色体异常
| [1] | Sepulveda W,Wong AE,Martinez-Ten P,et al. Retronasal triangle:a sonographic landmark for the screening of cleft palate in the first trimester [J]. Ultrasound Obstet Gynecol,2010,35(1)∶7-13 |
| [2] | 王丽敏,马小燕,江玮,等. 胎儿鼻后三角在妊娠早期筛查颜面部畸形中的应用价值[J].临床超声医学杂志,2014,6(16)∶369-372 |
| [3] | Martinez-ten P,Adiego B,Illescas T,et al. First-trimester diagnosis of cleft lip and palate using three-dimensional ultrasound [J]. Ultrasound Obstet Gynecol,2012,40(1)∶40-46 |
| [4] | 李元仙. 三维超声在胎儿畸形产前筛查中的应用价值[J].医学影像学杂志,2010,20(4)∶607 |
| [5] | Wilhelm L, Borgers H. The 'equals sign': a novel marker in the diagnosis of fetal isolated cleft palatef [J]. Ultrasound Obstet Gynec,2010,36(4)∶439-444 |
| [6] | 李胜利.胎儿畸形产前超声诊断学[M]. 北京:人民军医出版社,2008∶445 |
| [7] | 中国医师协会超声医师分会.产前超声检查指南(2012),J /CD]中华医学超声杂志:电子版,2012,9(7)∶574-580 |
| [8] | Saltvedt S,Almstrom H,Kublickas M,et al. Detection of malformations in chromosomally normal fetuses by routine ultrasound at 12 or 18 weeks of gestation-a randomised controlled trial in 39,572 pregnancies [J]. BJOG,2006,113(6)∶664-674 |
| [9] | 李胜利,欧阳淑媛,陈琮瑛,等.胎儿颜面部的产前超声研究[J].中华超声影像学杂志,2003,12(6)∶355-358 |
| [10] | TaiPale P,Ammala M,Salonen R,et al. Learning curve in ultrasonographic screening for selected fetal structural anomalies in early Pregnancy [J]. Obstet Gyneeol,2003,101(2)∶273-278 |
| [11] | Waldo Sepulveda,Tamara Illescas,Begona Adiego,et al. Prenatal Detection of Fetal Anomalies at the 11- to 13-Week Scan-Part I: Brain, Face and Neck [J]. Donald School Journal of Ultrasound in Obstetrics and Gynecology,2013,7(4)∶359-368 |
| [12] | TaiPale P,Ammala M,Salonen R,et al. Learning curve in ultrasonographic screening for selected fetal structural anomalies in early Pregnancy [J]. Obstet Gyneeol,2003,101(2)∶273-278 |
| [13] | Ghi T,Arcangeli D. Three-dimensional sonographic imaging of fetal bilateral cleft lip and palate in the first trimester [J]. Ultrasound Obstet Gynecol,2009,34(1)∶119-120 |
| [14] | 毕静如,李胜利,陈琮瑛,等.三平面正交超声扫查诊断胎儿唇腭裂的价值[J].中国妇幼保健,2005,20(16)∶2082-2083 |
| [15] | 朱玉蓉. 超声检查在胎儿产前唇腭裂畸形的诊断价值分析[J].国现代药物应用,2013,7(20)∶45-46 |
| [16] | Paladini D,Vassallo M,Sglavo G,et al. The role of spatio-temporal image correlation(STIC) with tomographic ultrasound imaging(TUI) in the sequential analysis of fetal congenital heart disease [J]. Ultrasound Obstet Gynecol,2006,27 (5)∶555-561 |
| [17] | 南欣荣,刘明,原光辉.山西人群亚甲基四氢叶酸还原酶基因C677T位点多态性与非综合性唇腭裂的相关性研究[J].华整形外科杂志,2014,30(4)∶265-269 |
| [18] | Shaikh D,Mercer NS, Sohan K,et al. Prenatal diagnosis of cleft lip and palate [J]. Br J Plast Surg,2001,54(4)∶288-289 |
