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-  2016 

纤维连接蛋白EDA片段的病理学研究进展
Pathologic Research Progress of Fibronectin EDA.

DOI: 10.13701/j.cnki.kqyxyj.2016.05.029

Keywords: EDA,纤维连接蛋白,可变剪接,

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Abstract:

摘要 细胞外基质纤维连接蛋白基因Ⅲ型重复序列有3个可变剪接区,分别为EDA、 EDB和IIICS。在肿瘤、胚胎及创伤愈合等细胞增殖和迁移活跃的组织中, EDA+FN呈高表达,而正常组织中几乎不表达。本文就其特性、生物学功能和临床应用前景进行综述

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