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- 2017
维药买朱尼对种植体周围炎龈沟液中白细胞介素-1β和牙周指数的影响
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Abstract:
摘要 目的:通过买朱尼对IL-1β有抑制作用机制尝试探讨维药买朱尼对种植体周围炎相关因子IL-1β和牙周指数的影响。方法:接受种植义齿修复的100名18～55岁患者分为标准对照组和实验组各50例,标准对照组术前口服阿莫西林;实验组术前口服阿莫西林,术后7 d拆线2组均测IL-1β、菌斑指数、出血指数。实验组口服4个疗程维药买朱尼。1个月后复诊测量IL-1β、菌斑指数、出血指数。应用SPSS 22.0进行数据统计分析。结果:对照组4周后IL-1β水平与1周后IL-1β水平相比显著下降(P<0.05),4周后出血指数与1周后出血指数相比显著下降(P<0.05),4周后菌斑指数与1周后菌板指数差异不显著;实验组4周后IL-1β水平与1周后IL-1β水平相比显著下降(P<0.05),4周后出血指数与1周后出血指数相比显著下降(P<0.05),4周后菌斑指数与1周后菌斑指数差异不显著。4周后,实验组IL-1β水平和出血指数显著低于对照组,菌斑指数无显著差异。结论:维药买朱尼对种植体周围龈沟液中IL-1β有抑制作用,对种植体周围炎症有很好的临床疗效
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