Luo L,Li DQ,Doshi A,et al.Experimental dry eye stimulates production of inflammatory cytokines and MMP-9and activates MAPK signaling pathways on the ocular surface[J].Invest Ophthalmol Vis sci,2004,45(12):4 293-4 301.
[2]
Chang F,Steelman Is,Shelton JG,et al.Regulation of cell cycle progression and apoptosis by the Ras,Raf,MEK/ERK pathway[J].Int J Oncol,2003,22(3):469-480.
[3]
Raison CL,Capuron L,Miller AH.Cytokines sing the blues:inflammation and the pathogenesis of depression[J].Trends Immunol,2006,27(1):24-31.
[4]
Han SB,Hyon JY,Woo SJ,et al.Prevalence of dry eye disease in an elderly Korean population[J].Arch Ophthalmol,2011,129(5):633-638.
[5]
Lin PY,Cheng CY,Hsu WM,et al.Association between symptoms and signs of dry eye among an elderly Chinese population in Taiwan:the Shihpai Eye Study[J].Invest Ophthalmol Vis Sci,2005,46(5):1 593-1 598.
[6]
Tang CH,Tsai CC.CCL2increases MMP-9expression and cell motility in human ehondrosarcoma cells via the Ras,Raf,MEK,ERK,NF-κB signaling pathway[J].Biochem Pharmacol,2012,83(3):335-344.
[7]
Schiffman RM,Walt JG,Jacobsen G,et al.Utility assessment among patients with dry eye disease[J].Ophthalmology,2003,110(7):1 412-1 419.
[8]
[No authors listed].Management and therapy of dry eye disease:Report of the management and therapy subcommittee of the international dry eye workshop[J].Ocul Surf,2007,5(2):163-178.
[9]
Paul A,Wilson S,Belham CM,et al.Stress-activated protein kinases:activation,regulation and function[J].Cell Signal,1997,9(6):403-410.
[10]
Pflugfelder SC,de Paiva CS,Tong L,et al.Stress-activated protein kinase signaling pathways in dry eye and ocular surface disease[J].Ocul Surf,2005,3(Suppl 4):154-157.
[11]
Li DQ,Luo L,Chen Z,et al.JNK and ERK MAP kinases mediate induction of IL-1beta,TNF-alpha and IL-8following hyperosmolar stress in human limbal epithelial cells[J].Exp Eye Res,2006,82(4):588-596.
[12]
Krishna M,Narang H.The complexity of mitogen-activated protein kinases(MAPKs)made simple[J].Cell Mol Life Sci,2008,65(22):3 525-3 544.
[13]
Ki WM,Sang BH,Eun RH,et al.Association between Depression and Dry Eye Disease in an Elderly Population[J].Invest Ophthalmol Vis Sci,2011,52(11):7 954-7 958.