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-  2016 

负压封闭引流技术治疗兔坐骨神经损伤 Treatment for Rabbit Sciatic Nerve Injury with Vacuum Sealing Drainage

Keywords: 负压封闭引流,,坐骨神经,修复

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Abstract:

目的:初步探讨负压封闭引流技术(VSD)治疗兔坐骨神经损伤的效果及机制。方法:随机将24只大白兔分2组。手术切除大白兔坐骨神经1cm并原位缝合。实验组用负压封闭引流技术治疗,对照组仅缝合伤口。术后比较两组大体观及神经电传导速度、小腿三头肌湿重恢复率、甲苯胺蓝染色、脑源性神经营养因子免疫组化及电镜观察。结果:术后1-2周两组均出现手术侧足部红肿、溃疡;术后4周及8周时,手术侧坐骨神经电传导速度检测显示实验组较对照组快,P<0.05;手术侧小腿三头肌与健侧小腿三头肌比值,实验组较对照组高,P<0.05;实验组免疫组化染色强度较对照组高,P<0.05;甲苯胺蓝染色及电镜观察示实验组较对照组明显生长。结论:VSD对周围神经损伤的修复有促进作用

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