D’Orazi G,Rinaldo C,Soddu S.Updates on Hipk2:A Resourceful oncosuppressor for clearing cancer[J].J Exp Clin Cancer Res,2012,31:63.
[2]
Lavra L,Rinaldo C,Ulivieri A,et al.The loss of the P53activator Hipk2is responsible for galectin-3overexpression in well differentiated thyroid carcinomas[J].PLoS One,2011,6(6):e20665.
[3]
Kuwano Y,Nishida K,Akaike Y,et al.Homeodomain-interacting protein kinase-2:a critical regulator of the DNA damage response and the epigenome[J].Int J Mol Sci,2016,17(10):pii:E1638.
[4]
de la Vega L,Grishina I,Moreno R,et al.A redoxregulated sumo/acetylation switch of Hipk2 controls the survival threshold to oxidative stress[J].Mol Cell,2012,46(4):472-483.
[5]
Chiocca S,Seiser C.Lifting the threshold between life and death:Sumo and Hdac fine-tune Hipk2to sense redox status[J].Mol Cell,2012,46(4):382-383.
[6]
van der Laden J,Soppa U,Becker W.Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases(Hipk)[J].Cell Commun Signal,2015,13:3.
[7]
Polonio-Vallon T,Kirkpatrick J,Krijgsveld J,et al.Src kinase modulates the apoptotic P53pathway by altering Hipk2localization[J].Cell Cycle,2014,13(1):115-125.
[8]
Siepi F,Gatti V,Camerini S,et al.Hipk2catalytic activity and subcellular localization are regulated by activation-loop Y354 autophosphorylation[J].Biochim Biophys Acta,2013,1 833(6):1 443-1 453.
[9]
Upadhyay M,Bhadauriya P,Ganesh S.Heat shock modulates the subcellular localization,stability,and activity of Hipk2[J].Biochem Biophys Res Commun,2016,472(4):580-584.
[10]
Zhou L,Feng Y,Jin Y,et al.Verbascoside promotes apoptosis by regulating Hipk2-P53signaling in human colorectal cancer[J].BMC Cancer,2014,14:747.
[11]
Wook Choi D,Yong Choi C.Hipk2 Modification Code for Cell Death and Survival[J].Mol Cell Oncol,2014,1(2):e955999.
[12]
de la Vega L,Frobius K,Moreno R,et al.Control of nuclear Hipk2localization and function by a sumo interaction motif[J].Biochim Biophys Acta,2011,1 813(2):283-297.
[13]
Tan M,Gong H,Zeng Y,et al.Downregulation of homeodomain-interacting protein kinase-2 contributes to bladder cancer metastasis by regulating Wnt signaling[J].J Cell Biochem,2014,115(10):1 762-1 767.
[14]
Cheng Y,Al-Beiti M,Wang J,et al.Correlation between homeodomain-interacting protein kinase 2 and apoptosis in cervical cancer[J].Mol Med Rep,2012,5(5):1 251-1 255.
[15]
Feng Y,Zhou L,Sun X,et al.Homeodomain-interacting protein kinase 2(Hipk2):apromising target for anti-cancer therapies[J].Oncotarget,2017,8(12):20 452-20 461.
[16]
Kwon MJ,Min SK,Seo J,et al.Hipk2Expression in progression of cutaneous epithelial neoplasm[J].Int J Dermatol,2015,54(3):347-354.
[17]
Saul VV,de la Vega L,Milanovic M,et al.Hipk2kinase activity depends on cis-autophosphorylation of its activation loop[J].J Mol Cell Biol,2013,5(1):27-38.
