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-  2018 

2型糖尿病冠状动脉非钙化性狭窄的危险因素分析 Analysis on Risk Factors for Stenosis of Non-Calcified Coronary Artery in Patients with Type 2 Diabetes Mellitus

Keywords: 高密度脂蛋白,非钙化病变,糖尿病,危险因素

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Abstract:

目的:探讨2型糖尿病冠状动脉非钙化性狭窄的危险因素。方法:收集2014-2017年本院2型糖尿病冠脉CT血管造影(CTA)非钙化性狭窄者的影像及临床资料进行回顾性分析。将病例分为明显狭窄组(≥50%)与不明显狭窄组(<50%),进行单因素及多因素回归分析,探讨冠脉非钙化性狭窄的相关因素。结果:符合纳入标准的病例共100例,其中不明显狭窄者70例(70%),明显狭窄者30例(30%)。单因素分析显示,男性、目前吸烟、饮酒、高密度脂蛋白(HDL)<1.03mmol/L和血红蛋白与冠脉明显狭窄有关(P<0.05);多因素回归分析显示HDL<1.03mmol/L是冠脉明显狭窄独立危险因素(OR=3.082,P=0.021)。HDL对预测冠脉明显狭窄具有较高的诊断准确率(AUC:0.802 8,95%CI0.737 2-0.868 4,P<0.000 1)。结论:HDL<1.03mmol/L是2型糖尿病冠状动脉非钙化狭窄的危险因素

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