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-  2017 

黏膜下注射联合氩离子凝固治疗慢性放射性肠病出血 Efficacy and Safety of Submucosal Injection Combined with Argon Plasma Coagualtion for Patients with Hemorrhagic Chronic Radiation Enteropathy

Keywords: 慢性放射性肠病,内镜,黏膜下注射,氩离子凝固

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Abstract:

目的:探讨黏膜下药物注射联合氩离子凝固治疗慢性放射性肠病出血的有效性和安全性。方法:对42例均经过药物灌肠或口服,其中3例加用高压氧治疗仍有顽固性出血者,应用结肠镜黏膜下注射联合氩离子凝固并随访,观察治疗前后便血情况、血红蛋白水平、病变面积和黏膜脆性,以及治疗后的并发症。结果:治疗后便血次数和量明显减少(P<0.005和P<0.000 1),血红蛋白水平明显上升(P<0.01),病变面积缩小和黏膜脆性减少(P<0.000 2或0.000 01)。除2例合并溃疡出血,40例经过1次或2次治疗,1次有效率87.5%(35/40),总有效率达100%(40/40)。40例随访期间(平均68.5个月)维持缓解。无严重的并发症。结论:内镜黏膜下药物注射联合氩离子凝固治疗慢性放射性肠病出血安全有效

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