Redler S,Albert F,Brockschmidt FF,et al.Investigation of selected cytokine genes suggests that IL2RA and the TNF/LTA locus are risk factors for severe alopecia areata[J].Br J Dermatol,2012,167(6):1 360-1 365.
[2]
Orru V,Tsai SJ,Rueda B,et al.A loss-of-function variant of PTPN22is associated with reduced risk of systemic lupus erythematosus[J].Hum Mol Genet,2009,18(3):569-579.
[3]
Hamza RT,Awwad KS,Temsah KA,et al.R620W polymorphism of protein tyrosine phosphatase PTPN22in Egyptian children and adolescents with systemic lupus erythematosus:relation to thyroid autoimmunity[J].Int J Adolesc Med Health,2013,25(2):143-149.
[4]
Ban Y,Tozaki T,Taniyama M,et al.The codon 620single nucleotide polymorphism of the protein tyrosine phosphatase-22gene does not contribute to autoimmune thyroid disease susceptibility in the Japanese[J].Thyroid,2005,15(10):1 115-1 118.
[5]
Piotrowski P,Lianeri M,Wudarski M,et al.Contribution of the R620 W polymorphism of protein tyrosine phosphatase non-receptor 22to systemic lupus erythematosus in Poland[J].Clin Exp Rheumatol,2008,26(6):1 099-1 102.
[6]
Kaufman KM,Kelly JA,Herring BJ,et al.Evaluation of the genetic association of the PTPN22R620Wpolymorphism in familial and sporadic systemic lupus erythematosus[J].Arthritis Rheum,2006,54(8):2 533-2 540.
[7]
Lea WW,Lee YH.The association between the PTPN22C1858T polymorphism and systemic lupus erythematosus:a meta-analysis update[J].Lupus,2011,20(1):51-57.
[8]
Smith SE,Neier SC,Davis TR,et al.Signaling protein complexes isolated from primary human skinresident T cells can be analyzed by Multiplex[J].Exp Dermatol,2014,23(4):272-273.
[9]
Alzolibani AA.Epidemiologic and genetic characteristics of alopecia areata[J].Acta Dermatovenerol Alp Panonica Adriat,2011,20(4):191-198.
[10]
Jailwala P,Waukau J,Glisic S,et al.Apoptosis of CD4+CD25(high)T cells in type 1diabetes may be partially mediated by IL-2deprivation[J].PLoS One,2009,4(8):e6527.
[11]
Cinek O,Hradsky O,Ahmedov G,et al.No independent role of the 1123G>C and+2740A>G variants in the association of PTPN22with type 1diabetes and juvenile idiopathic arthritis in two Caucasian populations[J].Diabetes Res Clin Pract,2007,76(2):297-303.
[12]
Taniyama M,Maruyama T,Tozaki T,et al.Association of PTPN22haplotypes with type 1diabetes in the Japanese population[J].Human Immunology,2010,71(8):795-798.
[13]
Huang JJ,Qiu YR,Li HX,et al.A PTPN22promoter polymorphism-1123G>C is associated with RA pathogenesis in Chinese[J].Rheum Int,2012,32(2):767-771.
[14]
Cloutier JF,Veillette A.Cooperative Inhibition of Tcell antigen receptor signaling by a complex between a kinase and a phosphatase[J].J Exp Med,1999,189(1):111-121.
[15]
Chang HH,Tai TS,Lu B,et al.PTPN22.6,a dominant negative isoform of PTPN22and potential biomarker of rheumatoid arthritis[J].PLoS One,2012,7(3):e33067.
[16]
Viatte S,Plant D,Bowes J,et al.Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients[J].Ann Rheum Dis,2012,71(12):1 984-1 990.
[17]
Pesenacker AM,Cook L,Levings MK.The role of FOXP3in autoimmunity[J].Current Opinion in Immunology,2016,43(16):16-23.
[18]
Rodriguez-Rodriguez L,Taib WR,Topless R,et al.The PTPN22R263Qpolymorphism is a risk factor for rheumatoid arthritis in Caucasian case-control samples[J].Arthritis Rheum,2011,63(2):365-372.
[19]
Zhebrun D,Kudryashova Y,Babenko A,et al.Association of PTPN22 1858T/T genotype with Type 1diabetes,Graves'disease but not with rheumatoid arthritis in Russian population[J].Aging,2011,3(4):368-373.
[20]
Wu H,Cantor RM,Graham DSC,et al.Association analysis of the R620Wpolymorphism of protein tyrosine phosphatase PTPN22in systemic lupus erythematosus families:increased t allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease[J].Arthritis Rheum,2005,52(8):2 396-2 402.
[21]
Bottini N,Stefanini L,Williams S,et al.Activation of ZAP-70through specific dephosphorylation at the inhibitory Tyr-292by the low molecular weight phosphotyrosine phospha-tase(LMPTP)[J].J Biol Chem,2002,277(27):24 220-24 224.
[22]
Banci M,Saccucci P,D'Annibale F,et al.ACP1genetic polymorphism and coronary artery disease:an association study[J].Cardiology,2009,113(4):236-242.
[23]
Tzall S,Ellenbogen A,Eng F,et al.Identification and characterization of nine RFLPs at the adenosine deaminase(ADA)locus[J].Am J Hum Genet,1989,44(6):864-875.
[24]
Gloria-Bottini F,Saccucci P,Banci M,et al.Effect of genetic factors on the association between coronary artery disease and PTPN22polymorphism[J].World J Cardiol,2014,6(6):376-380.
[25]
Diaz-Gallo LM,Espinopaisán L,Fransen K,et al.Differential association of two PTPN22 coding variants with Crohn’s disease and ulcerative colitis[J].Inflamm Bowel Dis,2011,17(11):2 287-2 294.
[26]
Wegienka G.Are uterine leiomyoma a consequence of a chronically inflammatory immune system[J].Med Hypotheses,2012,79(2):226-231.
[27]
Zheng K,Zhang J,Zhang P,et al.PTPN22and CTLA-4gene polymorphisms in resected thymomas and thymus for myasthenia gravis[J].Thorac Cancer,2012,3(4):307-312.
[28]
Liu J,Chen M,Li R,et al.Biochemical and functionalstudies of lymphoid-specific tyrosine phosphatase(Lyp)variants S201Fand R266W[J].PLoS One,2012,7(8):e43631.
[29]
叶娟.PTPN22基因多态性与Graves病[J].国际病理科学与临床杂志,2013,33(6):548-552.Ye J.PTPN22gene polymorphism and Graves disease[J].International Journal of Pathology and Clinical Medicine,2013,33(6):548-552.
[30]
Pertovaara M,Kh9nen M,Juonala M,et al.Auto-immunity and atherosclerosis:the presence of antinuclear antibodies is associated with decreased carotid elasticity in young women.The Cardiovascular Risk in Young Finns Study[J].Rheumatology(Oxford),2009,48(12):1 553-1 556.
Heneberg P,MaláM,Yorifuji T,Gat-Yablonski G,et al.Low frequencies of utoimmunity-ssociated PTPN22polymorphisms in MODY patients,including those transiently expressing Islet cell autoantibodies[J].Int Arch Allergy Immunol,2015,166(3):189-198.
[33]
Rodríguez A,Alfaro JM,Balthazar V,et al.Association analysis of PTPN22,CTLA4 and IFIH1 genes with type 1diabetes in Colombian families[J].J Diabetes,2015,7(3):402-410.
[34]
陈志涛,吴杰,王萍,等.蛋白酪氨酸磷酸酶非受体型基因多态性与溃疡性结肠炎的相关性[J].武汉大学学报:医学版,2013,21(15):1 462-1 467.Chen ZT,WU J,Wang P,et al.Association of Protein Tyrosine Phosphatase Nonreceptor Type 22 Gene-1123 G/C Polymorphism with Ulcerative Colitis[J].Medical Journal of Wuhan University,2013,34(5):719-723.
[35]
Ziegler AG,Pflueger M,Winkler M,et al.Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1diabetes in young children[J].J Autoimmun,2011,37(1):3-7.
[36]
Galán-Gutiérrez M,Rodríguez-Bujaldón A,MorenoGiménez JC,et al.Update on the treatment of alopecia areata[J].Actas Dermosifiliogr,2009,100(4):266-276.
[37]
Heneberg P,MaláM,Yorifuji T,et al.Low frequencies of autoimmunity-associated PTPN22 polymorphisms in MODY patients,including those transiently expressing islet cell autoantibodies[J].Int Arch Allergy Immunol,2015,166(3):189-198.
[38]
Manjarrez-Ordu珘no N,Marasco E,Chung SA,et al.CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation[J].Nat Genet,2012,44(11):1 227-1 230.
[39]
Rodríguez A,Alfaro JM,Balthazar V,et al.Association analysis of PTPN22,CTLA4 and IFIH1 genes with type 1diabetes in Colombian families[J].J Diabetes,2015,7(3):402-410.
[40]
Kisand K,Uibo R.LADA and T1Din Estonian population-two different genetic risk profiles[J].Gene,2012,497(2):285-291.
[41]
Ostanek L,Ostanek-Pańka M,Bobrowska-Snarska D,et al.PTPN22 1858C>T gene polymorphism in patients with SLE:association with serological and clinical results[J].Mol Biol Rep,2014,41(9):6 195-6 200.
[42]
Salinassantander M,Sánchezdomínguez C,Cantúsalinas C,et al.Association between PTPN22C1858Tpolymorphism and alopecia areata risk[J].Biochemical&Biophysical Research Communications,2015,8(21):602-609.
[43]
Sfar I,Aleya WB,Mouelhi L,et al.Lymphoid tyrosine phosphatase R620W variant and inflammatory bowel disease in Tunisia[J].World J Gastroenterol,2010,16(4):479-483.
[44]
Velaga MR,Wilson V,Jennings CE,et al.The codon620tryptophan allele of the lymphoid tyrosine phosphatase(LYP)gene is a major determinant of Graves’disease[J].J Clin Endocrinol Metab,2004,89(11):5 862-5 865.
[45]
Saccucci P,Banci M,Amante A,et al.Coronary artery disease:evidence of interaction between PTPN22and p53genetic polymorphisms[J].Cardiology,2011,120(3):166-168.
