PI3K/Akt通路在缺血后处理减轻小鼠肠缺血再灌注损伤中的作用 Role of PI3K/Akt Signal Pathway in the Protective Effect of Ischemia Postcondition on Intestinal Ischemia-Reperfusion-Induced Intestinal Injury
Wang G,Chen Z,Zhang F,et al.Blockade of PKCβprotects against remote organ injury induced by intestinal ischemia and reperfusion via a p66shc-mediated mitochondrial apoptotic pathway[J].Apoptosis Int J Program Cell Death,2014,19(9):1 342-1 353.
[2]
Cheng CH,Lin HC,Lai IR,et al.Ischemic postconditioning attenuate reperfusion injury of small intestine:impact of mitochondrial permeability transition[J].Transplantation,2013,95(4):559-565.
[3]
Weng X,Wang L,Chen Z,et al.Ischemic postconditioning inhibits apoptosis in an in vitro proximal tubular cell model[J].Mol Med Rep,2015,12(1):99-104.
[4]
Liu C,Shen Z,Liu Y,et al.Sevoflurane protects against intestinal ischemia-reperfusion injury partly by phosphatidylinositol 3kinases/Akt pathway in rats[J].Surgery,2015,157(5):924-933.
[5]
Tsutsumi YM,Tsutsumi R,Mawatari K,et al.Compound K,a metabolite of ginsenosides,inducescardiac protection mediated nitric oxide via Akt/PI3Kpathway[J].Life Sci,2011,88(15-16):725-729.
Nielsen C,Lindholt JS,Erlandsen EJ,et al.d-lactate as a marker of venous-induced intestinal ischemia:an experimental study in pigs[J].Int J Surg Lond Engl,2011,9(5):428-432.
[9]
Khadaroo RG,Fortis S,Salim SY,et al.I-FABP as biomarker for the early diagnosis of acute mesenteric ischemia and resultant lung injury[J].PLoS One,2014,9(12):e115 242.