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-  2017 

细胞融合与肿瘤关系研究进展 Research Progress of Relationship Between Cell Fusion and Tumor

Keywords: 细胞融合,机制,血管生成,肿瘤转移,上皮-间质转化,染色体非整倍性,肿瘤异质性

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Abstract:

细胞融合,是生物体在发展和达到动态平衡过程中产生的。而肿瘤的发展是一个多步骤的复杂过程,从肿瘤的发生及生长,到肿瘤发生转移,这些过程都与细胞融合关系密切。目前对细胞融合与肿瘤之间关系的研究较多,主要集中于几个方面:细胞融合研究机制;不同细胞之间的融合;细胞融合与其它学说如上皮-间质转化(EMT)、染色体非整倍性、肿瘤异质性等之间的关系;细胞融合与血管生成和肿瘤转移的研究等等。本文主要从以上几个方面入手,初步探究细胞融合与肿瘤之间的关系,从而为肿瘤治疗提供新的目标和方向

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