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-  2015 

量子点标记探针技术在乳腺癌中的应用进展 Advances of Quantum Dot-Based Nanotechnology in Breast Cancer Research

Keywords: 量子点,分子成像,乳腺癌,肿瘤标记物,亚分类,肿瘤侵袭模式

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Abstract:

乳腺癌为高度异质性恶性肿瘤,不同亚型的乳腺癌预后可以有很大差别。单纯依靠形态病理学或现有的以半定量分析和主观判断为基础的方法对于乳腺癌的预后判断和分类显得不够全面,纳米量子点标记探针分子成像技术因其独特的光化学优势,在乳腺癌的基础和临床研究中显示良好前景。本文就纳米量子点标记探针分子成像技术运用于乳腺癌分子标记物的检测、乳腺癌亚分类方法及预后评估、乳腺癌侵袭模式及浸润微环境等的研究作一综述,同时本文还总结了量子点的特性和最新研究热点及其在乳腺癌研究中面临的挑战和未来发展趋势

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