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-  2018 

癫痫儿童行为问题及情绪障碍研究 A Survey on Behavioral and Emotional Disorders in Children with Epilepsy

Keywords: 癫痫,共患病,行为问题,焦虑,抑郁

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Abstract:

目的:评估癫痫儿童的行为问题及情绪障碍,并分析其相关因素。方法:采用Conners父母用问卷(PSQ)、焦虑自评量表(SAS)、抑郁自评量表(SDS)对癫痫儿童及正常儿童进行行为问题及情绪障碍评估,分析影响癫痫儿童行为及情绪的可能因素。结果:共纳入癫痫组50例,正常对照组52例;癫痫组男女比例27/23,平均年龄(8.25±2.54)岁;对照组男女比例27/25,平均年龄(8.62±2.55)岁。行为问题方面,癫痫组在品行问题、学习问题、心身问题、冲动-多动、焦虑、多动指数等方面与对照组的差异均存在统计学意义。情绪障碍方面,癫痫组的SAS量表标准分高于对照组,焦虑检出率为12.0%,对照组检出率为3.8%,差异均无统计学意义。癫痫组的SDS量表标准分高于对照组,抑郁检出率为26.0%,对照组检出率为3.8%,差异均有统计学意义。癫痫儿童无焦虑组的品行问题、冲动-多动、焦虑、多动指数因子得分均高于健康儿童无焦虑组,而癫痫儿童伴焦虑组的学习问题、心身问题、多动指数均高于健康儿童无焦虑组,差异均具有统计学意义;癫痫儿童伴抑郁组的品行问题、学习问题、心身问题、冲动-多动、多动指数因子得分高于健康儿童无抑郁组,癫痫儿童无抑郁组的品行问题、冲动-多动、多动指数因子得分高于健康儿童无抑郁组,差异均具有统计学意义。剖宫产、发作频率、抑郁是影响癫痫患儿行为问题的危险因素,OR(95%CI)分别为14.899(1.750-126.874)、3.100(1.397-6.876)、10.595(1.077-104.272)。结论:癫痫儿童较正常儿童更易出现行为异常及情绪障碍,且情绪障碍以抑郁为主。癫痫主要影响内在行为,焦虑及抑郁主要影响外在行为,癫痫共患焦虑及抑郁可加重多动异常。剖宫产、发作频率、抑郁是影响癫痫患儿行为问题的危险因素

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