全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

更多...
-  2017 

立体定向活检术在AIDS伴发颅内病变诊断中的应用 Application of Stereotactic Biopsy for the Diagnosis of the Intracranial Lesions in Patients with AIDS

Keywords: 立体定向活检术,艾滋病,颅内病变

Full-Text   Cite this paper   Add to My Lib

Abstract:

目的:总结立体定向活检术在诊断艾滋病(AIDS)伴发颅内病变诊断中的经验,探讨手术方法及技术要点、如何降低手术并发症以及提高阳性诊断率。方法:回顾性分析7例行脑立体定向活检术AIDS伴发颅内病变患者(男4例,女3例;年龄15-49岁),病史1月-1年。均行核磁共振定位立体定向脑活检术,活检标本术后行常规HE染色及免疫组化病理学检查。结果:7例患者手术顺利,病理结果示:脑弓形虫病2例,隐球菌脑炎2例,巨细胞脑炎2例,结核性脓肿1例,星形细胞瘤1例,其中1例为脑弓形虫病和隐球菌脑炎共同感染。诊断成功率100%,术后并发症率14.3%(1/7),无死亡。术后随访6月-6年,1例完全康复,4例症状明显好转,2例死亡。结论:立体定向活检术是诊断AIDS伴发颅内病变安全、有效的方法,有助于协助诊断、制定治疗方案和改善预后

References

[1]  Rosenow JM,Hirschfeld A.Utility of brain biopsy in patients with acquired immunodeficiency syndrome before and after introduction of highly active antiretroviral therapy[J].Neurosurgery,2007,61(1):130-141.
[2]  Shakal AA,Mokbel EA.Hemorrhage after stereotactic biopsy from intra-axial brain lesions:incidence and avoidance[J].J Neurol Surg A Cent Eur Neurosurg,2014,75(3):177-182.
[3]  Zibly Z,Levy I,Litchevski V,et al.Brain biopsy in AIDS patients:diagnostic yield and treatment applications[J].AIDS Res Ther,2014,11(1):4.
[4]  Reithmeier T,Lopez WO,Doostkam S,et al.Intraindividual comparison of histopathological diagnosis obtained by stereotactic serial biopsy to open surgical resection specimen in patients with intracranial tumours[J].Clin Neurol Neurosurg,2013,115(10):1 955-1 960.
[5]  Gildenberg PL,Gathe JC,Kim JH.Stereotactic biopsy of cerebral lesions in AIDS[J].Clin Infect Dis,2000,30(3):491-499.
[6]  Waters JD,Gonda DD,Reddy H,et al.Diagnostic yield of stereotactic needle-biopsies of sub-cubic centimeter intracranial lesions[J].Surg Neurol Int,2013,4(Suppl3):S176-S181.
[7]  Nicolato A,Gerosa M,Piovan E,et al.Computerized tomography and magnetic resonance guided stereotactic brain biopsy in nonimmunocompromised and AIDS patients[J].Surg Neurol,1997,48(3):267-277.
[8]  Skolasky RL,Dal Pan GJ,Olivi A,et al.HIV-associated primary CNS lymorbidity and utility of brain biopsy[J].J Neurol Sci,1999,163(1):32-38.
[9]  Antinori A,Ammassari A,Luzzati R,et al.Role of brain biopsy in the management of focal brain lesions in HIV-infected patients.Gruppo Italiano Cooperativo AIDS&Tumori[J].Neurology,2000,54(4):993-997.
[10]  Li HJ,Li YF,Li N,et al.Clinical manifestations of imaging demonstrations of AIDS-related nervous system infections[J].Chin Med J(Engl),2013,126(22):4 371-4 379.

Full-Text

Contact Us

service@oalib.com

QQ:3279437679

WhatsApp +8615387084133