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-  2015 

湖北地区13例眼眶转移癌的临床分析 Metastatic Orbital Tumors:Clinical Analysis of 13 Cases in Hubei

Keywords: 眼眶,转移,肺癌,

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Abstract:

目的:探讨湖北地区13例眼眶转移癌的原发部位、影像学表现、治疗转归等临床特征。方法:回顾性分析武汉大学人民医院眼科中心2000年12月至2014年12月期间经过手术后病理明确诊断的13例眼眶转移癌的临床表现、原发部位和影像学表现等。结果:这项研究包括8名男性和5名女性,年龄范围36-72岁(平均50.4岁)。所有的患者来自湖北地区。其中原发肿瘤最常见的是肺癌5例(38.5%),其次是乳腺癌2例(15.4%),肝癌2例(15.4%),胃癌、结肠癌、甲状腺癌、子宫恶性平滑肌肉瘤各1例(7.7%)。最常见的临床表现是眼球突出(84.6%)、眼球运动受限(69.2%)、复视(61.5%)、眼睑肿胀(38.5%)、视力下降(38.5%)和结膜充血(23.1%)。主要治疗包括手术切除、放疗、全身化疗和观察。有随访资料的10例(76.9%)患者(平均随访时间23.5个月)。结论:在湖北地区眼眶转移癌最常见的原发性癌症为肺癌,其次是乳腺癌和肝癌。眼眶转移癌可有多种临床表现,全身性肿瘤患者出现上述临床表现时需考虑此病。该病的预后普遍较差,手术可以改善其生存质量

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