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-  2015 

细胞外基质的硬度与细胞生物学功能的研究进展 Research Progress of Biological Function and Rigidity of Extracellular Matrix

Keywords: 细胞外基质硬度,力学相关性,细胞迁移,细胞核形态,基因转移,信号转导

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Abstract:

细胞外基质是细胞赖以生存的环境,细胞外基质中物质和代谢的不平衡导致细胞外基质硬度的变化,从而能够影响细胞的一系列生物学功能。本文阐述了近期关于细胞外基质的改变与力学相关性的研究,以及其对细胞的迁移、细胞核形态的改变、细胞分化、基因转移、细胞的信号转导方面的影响

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