CYLD抑制自噬提高膀胱癌细胞吉西他滨化疗敏感性
CYLD improves bladder cancer gemcitabine chemosensitivity via suppressing autophagy

DOI: 10.6040/j.issn.1671-7554.0.2016.378

Keywords: CYLD基因,膀胱肿瘤,吉西他滨,自噬,化疗敏感性,
CYLD gene,Chemosensitivity,Autophagy,Bladder cancer,Gemcitabine

Full-Text   Cite this paper   Add to My Lib

Abstract:

References

[1]	Zhao Y, Ma CA, Wu L, et al. CYLD and the NEMO zinc finger regulate tumor necrosis factor signaling and early embryogenesis[J]. J Biol Chem, 2015, 290(36):22076-22084.
[2]	Liu S, Xie F, Wang H, et al. Ubenimex inhibits cell proliferation, migration and invasion in renal cell carcinoma:the effect is autophagy-associated[J]. Oncol Rep, 2015, 33(3):1372-1380.
[3]	向波, 易梅, 李小玲, 等. 细胞自噬在肿瘤发生发展中的作用[J]. 生物化学与生物物理进展, 2012, 3:241-249. XIANG Bo, YI Mei, LI Xiaoling, et al. Progress on role of autophagy in cancer[J]. Progress in Biochemistry and Biophysics, 2012, 3:241-249.
[4]	Ozpolat B, Benbrook DM. Targeting autophagy in cancer management-strategies and developments[J]. Cancer Manag Res, 2015, 7:291-299.
[5]	Bauckman KA, Mysorekar IU. Ferritinophagy drives uropathogenic Escherichia coli persistence in bladder epithelial cells[J]. Autophagy, 2016, 12(5):850-863.
[6]	Hunstig F, Schulz S, Nieten I, et al. A case of Brooke-Spiegler syndrome with a novel mutation in the CYLD gene in a patient with aggressive non-Hodgkin's lymphoma[J]. J Cancer Res Clin Oncol, 2016, 142(4):845-848.
[7]	Zhang Y, Sun Y, Chen T, et al. Genetic variations rs11892031 and rs401681 are associated with bladder cancer risk in a Chinese population[J]. Int J Mol Sci, 2014, 15(11):19330-19341.
[8]	Sun L, Lu J, Niu Z, et al. A Potent chemotherapeutic strategy with Eg5 inhibitor against gemcitabine resistant bladder cancer[J]. PLoS One, 2015, 10(12):e14484-14499.
[9]	Ni F, Zhao H, Cui H, et al. MicroRNA-362-5p promotes tumor growth and metastasis by targeting CYLD in hepatocellular carcinoma[J]. Cancer Lett, 2015, 356(2 Pt B):809-818.
[10]	Desantis CE, Lin CC, Mariotto AB, et al. Cancer treatment and survivorship statistics, 2014[J]. CA Cancer J Clin, 2014, 64(4):252-271.
[11]	Stein JP, Lieskovsky G, Cote R, et al. Radical cystectomy in the treatment of invasive bladder cancer:long-term results in 1,054 patients[J]. J Clin Oncol, 2001, 19(3):666-675.
[12]	Bignell GR, Warren W, Seal S, et al. Identification of the familial cylindromatosis tumour-suppressor gene[J]. Nat Genet, 2000, 25(2):160-165.
[13]	Sun B, Li L, Ma W, et al. MiR-130b inhibits proliferation and induces apoptosis of gastric cancer cells via CYLD[J]. Tumour Biol, 2016, 37(6):7981-7987.
[14]	Yang JM, Xu Z, Wu H, et al. Overexpression of extracellular matrix metalloproteinase inducer in multidrug resistant cancer cells[J]. Mol Cancer Res, 2003, 1(6):420-427.
[15]	Liu S, Lv J, Han L, et al. A pro-inflammatory role of deubiquitinating enzyme cylindromatosis(CYLD)in vascular smooth muscle cells[J]. Biochem Biophys Res Commun, 2012, 420(1):78-83.
[16]	Klionsky DJ, Abdelmohsen K, Abe A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy(3rd edition)[J]. Autophagy, 2016, 12(1):1-222.
[17]	Chen L, Ye HL, Zhang G, et al. Autophagy inhibition contributes to the synergistic interaction between EGCG and doxorubicin to kill the hepatoma Hep3B cells[J]. PLoS One, 2014, 9(1):e85771-85783.

Full-Text