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- 2017
培哚普利通过调节Akt-FoxO1通路保护糖尿病性心肌病大鼠心功能损伤
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Abstract:
[1] | Tarquini R, Lazzeri C, Pala L, et al. The diabetic cardiomyopathy[J]. Acta Diabetol, 2011, 48(3):173-181. |
[2] | Devereux RB, Roman MJ, Paranicas M, et al. Impact of diabetes on cardiac structure and function:the strong heart study[J]. Circulation, 2000, 101(19):2271-2276. |
[3] | Battiprolu PK, Hojayev B, Jiang N, et al. Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice[J]. J Clin Invest, 2012, 122(3):1109-1118. |
[4] | Cal L, Li W, Wang G, et al. Hyperglycemia-induced apoptosis in mouse myocardium:mitochondrial cytochrome C-mediated caspase-3 activation pathway[J]. Diabetes, 2002, 51(6):1938-1948. |
[5] | Fiordaliso F, Li B, Latini R, et al. Myocytes death in streptozotocin-induced diabetes in rats is angiotensin II-dependent[J]. Lab Invest, 2000, 80(4):531-527. |
[6] | Sun JY, Zhai L, Li QL, et al. Effects of ACE inhibition on endothelial progenitor cell mobilization and prognosis after acute myocardial infarction in type 2 diabetic patients[J]. Clinics, 2013, 68(5):665-673. |
[7] | 林雪,方理刚.糖尿病与心力衰竭[J].临床内科杂志,2016, 33(4):227-231. |
[8] | Qu Z, Xu H, Tian Y. Effects of angiotensin-converting enzyme inhibition and bradykinin peptides in rats with myocardial infarction[J]. Int J Clin Exp Pathol, 2015, 8(3):3410-3417. |
[9] | Zhang JN, Geng Q, Chen XJ, et al. Alteration of endothelin system and calcium handling protein in left ventricles following drug treatment in dilated cardiomyopathy rats[J]. Acta Pharmacol Sin, 2003, 24(11):1099-1102. |
[10] | Wang CH, Verma S, Hsieh IC, et al. Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system[J]. J Mol Cell Cardiol, 2006, 41(1):34-43. |
[11] | McConnell KJ, Humphries TL, Raebel MA, et al. Clinical pharmacy specialist implementation of lisinopril therapy in patients with coronary artery disease and diabetes mellitus[J]. Pharmacotherapy, 2003, 23(12):1564-1572. |
[12] | 李春霞, 黄宝群. 培哚普利与美托洛尔诊治糖尿病无症状心功能不全50例的临床效果观察[J]. 糖尿病新世界, 2014, 8(5):23. |
[13] | 钟惠菊, 周敏, 吴小英, 等. 培哚普利对STZ糖尿病大鼠心肌保护作用的实验研究[J].中国临床保健杂志, 2001, 4(2):106-109. ZHONG Huiju, ZHOU Min, WU Xiaoying, et al. An experimental study on the cardial protective effect of perindopril in diabetic rats[J]. J Clin Healthcare, 2001, 4(2):106-109. |
[14] | Kong X, Zhang L, Hua X, et al. Squamosamide derivative FLZ protects pancreatic β-Cells from glucotoxicity by stimulating Akt-FOXO1 pathway[J]. Diabetes Res, 2015:803986-803995. doi:10.1155/2015/803986. |
[15] | Puthanveetil P, Wan A, Rodrigues B. FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival[J]. Cardiovasc Res, 2012, 97(3):393-403. |
[16] | Kitamura T, Nakae J, Kitamura Y, et al.The forkhead transcription factor Foxo1 links insulin signalingtoPdx1 regulation of pancreatic βcell growth[J]. J Clin Invest, 2002, 110(12):1839-1847. |
[17] | 赵航,冯景辉,吴秀萍.糖尿病心肌病发病机制的研究[J].国际心血管病杂志,2016, 43(1):16-18. |
[18] | Asbun J, Villarreal FJ. The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy[J].J Am CollCardiol, 2006, 47(4):693-700. |
[19] | 中华医学会心血管病学分会, 中华心血管病杂志编辑委员会. 血管紧张素转换酶抑制剂在心血管病中应用专家共识[J]. 中华心血管病杂志,2007,35(2):97-106. Chinese Society of Cardiology of Chinese Medical, Editorial board of Chinese Journal of Cardiology. Chinese expert consensus document on angiotensin converting enzyme inhibitors in cardiovascular diseases[J]. Chinese Journal of Cardiology, 2007, 35(2):97-106. |
[20] | Gross DN, Wan M, Birnbaum MJ. The role of FOXO in the regulation of metabolism[J].Curr Diab Rep, 2009, 9(3):208-214. |
[21] | Dharaneeswaran H, Abid MR, Yuan L, et al. FOXO1-mediated activation of Aktplays a critical role in vascular homeostasis[J]. Circ Res, 2014, 115(2):238-251. |