人乳腺癌细胞系MCF-7中FOXM1调控SYK转录
FOXM1 regulates transcription of SYK in breast cancer cell line MCF-7

DOI: 10.6040/j.issn.1671-7554.0.2016.187

Keywords: MCF-7细胞,叉头框转录因子M1,转录调控,乳腺肿瘤,脾酪氨酸激酶,
MCF-7 cells,Forkhead box protein M1,Transcriptional regulation,Breast cancer,Spleen tyrosine kinase

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[1]	Sung YM, Xu X, Sun J, et al. Tumor suppressor function of SYK in human MCF10A in vitro and normal mouse mammary epithelium in vivo[J]. PLoS One, 2009, 4(10): e7445. doi:10.1371 /journal.pone.0007445.
[2]	Zhang X, Shrikhande U, Alicie BM, et al. Role of the protein tyrosine kinase SYK in regulating cell-cell adhesion and motility in breast cancer cells[J]. Mol Cancer Res, 2009, 7(5): 634-644.
[3]	Yuan Y, Mendez R, Sahin A, et al. Hypermethylation leads to silencing of the SYK gene in human breast cancer[J]. Cancer Res, 2001, 61(14): 5558-5561.
[4]	Shin SH, Lee KH, Kim BH, et al. Downregulation of spleen tyrosine kinase in hepatocellular carcinoma by promoter CpG island hypermethylation and its potential role in carcinogenesis[J]. Lab Invest, 2014, 94(12): 1396-1405.
[5]	Teh MT, Gemenetzidis E, Patel D, et al. FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma[J]. PLoS One, 2012, 7(3): e34329. doi: 10.1371/journal.pone.0034329. Epub 2012 Mar 26.
[6]	Ning Z, Wang A, Liang J, et al. USP22 promotes the G1/S phase transition by upregulating FOXM1 expression via beta-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma[J]. Int J Oncol, 2014, 45(4): 1594-1608.
[7]	Li J, Sidell N. Growth-related oncogene produced in human breast cancer cells and regulated by Syk protein-tyrosine kinase[J]. Int J Cancer, 2005, 117(1): 14-20.
[8]	Yu M, Tang Z, Meng F, et al. Elevated expression of FOXM1 promotes the tumor cell proliferation in hepatocellular carcinoma[J]. Tumour Biol, 2016, 37(1):1289-1297.
[9]	Baranski OA, Kalinichenko VV, Adami GR. Increased FOXM1 expression can stimulate DNA repair in normal hepatocytes in vivo but also increases nuclear foci associated with senescence[J]. Cell Prolif, 2015, 48(1): 105-115.
[10]	Song IS, Jeong YJ, Jeong SH, et al. FOXM1-induced PRX3 regulates stemness and survival of colon cancer cells via maintenance of mitochondrial function[J]. Gastroenterology, 2015, 149(4): 1006-1016.
[11]	Katz E, Dubois-Marshall S, Sims AH, et al. A gene on the HER2 amplicon, C35, is an oncogene in breast cancer whose actions are prevented by inhibition of SYK[J]. Br J Cancer, 2010, 103(3): 401-410.
[12]	Abram, CL, Lowell CA, The expanding role for ITAM-based signaling pathways in immune cells[J]. Sci STKE, 2007, 2007(377): re2. doi: 10.1126 /stke.3772007re2.
[13]	Geahlen RL.SYK and pTyrd: Signaling through the B cell antigen receptor[J]. Biochim Biophys Acta, 2009, 1793(7): 1115-1127.
[14]	Wonsey DR, Follettie MT. Loss of the forkhead transcription factor FOXM1 causes centrosome amplification and mitotic catastrophe[J]. Cancer Res, 2005, 65(12): 5181-5189.
[15]	Ahmad A, Wang Z, Kong D, et al. FOXM1 down-regulation leads to inhibition of proliferation, migration and invasion of breast cancer cells through the modulation of extra-cellular matrix degrading factors[J]. Breast Cancer Res Treat, 2010, 122(2): 337-346.
[16]	Hong J, Yuan Y, Wang J, et al. Expression of variant isoforms of the tyrosine kinase SYK determines the prognosis of hepatocellular carcinoma[J]. Cancer Res, 2014, 74(6): 1845-1856.
[17]	Krisenko MO, Geahlen RL. Calling in SYK: SYKs dual role as a tumor promoter and tumor suppressor in cancer[J]. Biochim Biophys Acta, 2015, 1853(1): 254-263.
[18]	Siegel RL, Fedewa SA, Miller KD, et al. Cancer statistics for Hispanics/Latinos, 2015[J]. CA Cancer J Clin, 2015, 65(6): 457-480.
[19]	Pfister NT, Fomin V, Regunath K, et al. Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells[J]. Genes Dev, 2015, 29(12): 1298-1315.
[20]	Wang N, Ding H, Liu C, et al. A novel recurrent CHEK2 Y390C mutation identified in high-risk Chinese breast cancer patients impairs its activity and is associated with increased breast cancer risk[J]. Oncogene, 2015, 34(40): 5198-5205.
[21]	盖领, 茅国新, 赵铃铃, 等. FOXM1在人乳腺癌组织和MCF-7细胞中的表达及临床意义[J]. 基础医学与临床, 2015, 35(8): 1100-1105. GAI Ling, MAO Guoxin, ZHAO Lingling, et al. Expression and clinical significance of FOXM1 in breast cancer tissues and MCF-7 cells[J]. Basic & Clinical Medicine, 2015, 35(8): 1100-1105.
[22]	田甜甜, 李际盛, 王亚伟, 等. 染料木黄酮在小细胞肺癌H446细胞中通过抑制FoxM1通路发挥抗肿瘤作用[J]. 山东大学学报(医学版), 2013, 51(6): 44-48. TIAN tiantian, LI jisheng, WANG Yawei, et al. Genistein exerts anti-tumor effects in small cell lung cancer H446 cells via suppressing the activity of FoxM1 pathway[J]. Journal of Shandong University(Health Science), 2013, 51(6): 44-48.
[23]	张红雨, 费立明, 王长亮, 等. 胰腺癌SYK表达与病理分期及血管生成的相关性[J]. 山东大学学报(医学版), 2008, 46(9): 880-883. ZHANG Hongyu, FEI Liming, WANG Changliang, et al. Correlations of SYK with pathology and angiogenesis of pancreatic adenocarcinoma[J]. Journal of Shandong University(Health Science), 2008, 46(9): 880-883.
[24]	Wang S, Ding YB, Chen GY, et al. Hypermethylation of SYK gene in promoter region associated with oncogenesis and metastasis of gastric carcinoma[J]. World J Gastroenterol, 2004, 10(12): 1815-1818.

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