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-  2017 

Nod样受体蛋白3炎性体在2型糖尿病脑微血管内皮细胞中的变化及变化机制
Expression changes and mechanism of Nod-like receptor protein 3 inflammasome in the cerebral microvascular endothelial cells in type 2 diabetes mellitus

DOI: 10.6040/j.issn.1671-7554.0.2016.1591

Keywords: Nod样受体蛋白3炎性体,2型糖尿病,脑微血管内皮细胞,硫氧还蛋白交互蛋白,活性氧,
Type 2 diabetes mellitus
,Reactive oxygen species,Nod-like receptor protein 3 inflammasome,Cerebral microvascular endothelial cells,Thioredoxin interacting protein

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[1]  Prasad S, Naik P, Cucullo L, et al. Diabetes mellitus and blood-brain barrier dysfunction: an overview[J]. J Pharmacovigil, 2014, 2(2): 125.
[2]  Umegaki H, Hayashi T, Nomura H, et al. Cognitive dysfunction: an emerging concept of a new diabetic complication in the elderly [J]. Geriatr Gerontol Int, 2013, 13(1): 28-34.
[3]  Price TO, Eranki V, Banks WA, et al. Topiramate treatment protects blood-brain barrier pericytes from hyperglycemia-induced oxidative damage in diabetic mice [J]. Endocrinology, 2012, 153(1): 362-372.
[4]  Shah GN, Morofuji Y, Banks WA, et al. High glucose-induced mitochondrial respiration and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrases: Implications for cerebral microvascular disease in diabetes [J]. Biochem Biophys Res Commun, 2013, 440(2): 354-358.
[5]  Oslowski CM, Hara T O, Sullivan-Murphy B, et al. Thioredoxin-interacting protein mediates ER stress-induced beta cell death through initiation of the inflammasome [J]. Cell Metab, 2012, 16(2): 265-273.
[6]  谢荣辉, 周师洁, 殷明. N-乙酰半胱氨酸对过氧化氢诱导的骨髓间充质干细胞凋亡的保护及作用机制研究[J]. 中国药理学通报, 2014, 30(1): 54-59.
[7]  Sun YN, Liu LB, Xue YX, et al. Effects of insulin combined with idebenone on blood-brain barrier permeability in diabetic rats [J]. J Neurosci Res, 2015, 93(4): 666-677.
[8]  Soares E, Prediger RD, Nunes S, et al. Spatial memory impairments in a prediabetic rat model [J]. Neuroscience, 2013, 250(10): 565-577.
[9]  Yunpeng D, Casey MM, Kern T, et al. Hyperglycemia increases mitochondrial superoxide in retina and retinal cells [J]. Free Radic Biol Med, 2003, 35(11): 1491-1499.
[10]  Shaked M, Kaiser N, Leibowitz G, et al. Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets [J]. Diabetologia, 2009, 52(4): 636-644.
[11]  Saedi E, Gheini MR, Faiz F, et al. Diabetes mellitus and cognitive impairments [J]. World J Diabetes, 2016, 7(17): 412-422.
[12]  Bauernfeind F, Hornung V. Of inflammasomes and pathogens - sensing of microbes by the inflammasome [J]. EMBO Mol Med, 2013, 5(6): 814-826.
[13]  Chen KH, Zhang JG, Zhang WW, et al. ATP-P2X4 signaling mediates NLRP3 inflammasome activation: a novel pathway of diabetic nephropathy [J]. Int J Biochem Cell Biol, 2013, 45(5): 932-943.
[14]  Latz E, Xiao TS, Stutz A, et al. Activation and regulation of the inflammasomes [J]. Nat Rev Immunol, 2013, 13(6): 397-411.
[15]  Yang F, Wang Z, Wei X, et al. NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke [J]. J Cereb Blood Flow Metab, 2014, 34(4): 660-667.
[16]  Lima HJr, Jacobson LS, Goldberg MF, et al. Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death [J]. Cell Cycle, 2013, 12(12): 1868-1878.
[17]  Lane T, Flam B, Lockey R, et al. TXNIP shuttling: missing link between oxidative stress and inflammasome activation [J]. Front Physiol, 2013, 4: 50.
[18]  Zhou R, Tardivel A, Thorens B, et al. Thioredoxin-interacting protein links oxidative stress to inflammasome activation [J]. Nat Immunol, 2010, 11(2): 136-140.
[19]  Brownlee M. Biochemistry and molecular cell biology of diabetic complications [J]. Nature, 2001, 13(414): 813-840.
[20]  Wang P, Huang R, Lu S, et al. RAGE and AGEs in mild cognitive impairment of diabetic patients: a cross-sectional study [J]. PLoS One, 2016, 11(1): 0145521. doi:10.1371.
[21]  Gombault A, Baron L, Couillin I, et al. ATP release and purinergic signaling in NLRP3 inflammasome activation [J]. Front Immunol, 2012, 3(11): 414.

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