药物性牙龈增生与细胞增殖和凋亡相关性的研究进展
Research progress on the relevance between drug-induced gingival overgrowth and cell proliferation and apoptosis

摘要： 药物性牙龈增生是指长期服用某些药物（如钙通道阻滞剂、抗癫痫药物和免疫抑制剂）为主要因素而诱发的牙龈体积增大,其发病机制尚未完全明确。近年来研究发现,牙龈增生与细胞的增殖和凋亡有密切关系,本文就药物性牙龈增生与细胞增殖和凋亡的相关性研究进展进行综述。
Abstract: Patients who received a long-term drug therapy, including calcium channel blockers, antiepileptic and immunosuppressive drugs, often suffered from drug-induced gingival overgrowth (DIGO). However, the pathogenesis of DIGO remains unclear to date. A number of research found that DIGO is relevant to apoptosis and cell proliferation. Research progress on the relevance between drug-induced gingival overgrowth and the apoptosis and cell proliferation is summarised in this paper.
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