出生队列研究在口腔医学中的应用
Use of birth cohort study in dental research

摘要： 队列研究是流行病学研究中可信度较高的研究方法之一，对于揭示疾病发生的病因具有重要的科学价值和理论意义。出生队列作为其中的典型研究方式，具有病因学证据强度高、可获得人群基线资料、可证实预防措施的有效性等不可比拟的优势。因此，在口腔医学研究中开展出生队列研究对于口腔疾病的预防有着重大意义。本文详细介绍了3个国家较为大型的包括口腔医学研究的出生队列研究的方法与研究内容，并且回顾了这些研究的主要研究成果。
Abstract: Cohort studies are highly reliable bases for epidemiological research to reveal the relationships between disease causes and effects. As a typical design, a birth cohort study provides significant advantages over other cohort studies. For instance, birth cohort studies generate high-quality etiological evidence and easily provide baseline data. Such studies also help confirm the effectiveness of preventive measures. Therefore, a birth cohort study on the prevention of oral diseases should be established in dental research. This paper aims to introduce the methods and contents of three large scale birth cohort studies from three different countries. This paper also aims to review the main research outcomes of these studies.
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