涎腺腺样囊性癌中上皮间充质转化分子调控机制的研究进展
Research progress on the mechanism of epithelial-mesenchymal transition in salivary adenoid cystic carcinoma

摘要： 涎腺腺样囊性癌（SACC）是最常见的涎腺恶性肿瘤之一，具有嗜神经侵袭和肺高转移特性，虽然生长缓慢，但其侵袭性强，预后差。近年来国内外学者对SACC发生上皮间充质转化（EMT）进行了大量的研究，以期探讨SACC发生发展、侵袭和远处转移的机制，启发临床治疗新思路。本文就SACC中EMT发生机制的研究进展作一综述。
Abstract: Salivary adenoid cystic carcinoma(SACC) is one of the most malignant tumors in salivary adenoid tissue with a feature of perineural invasion, lung metastasis, which grows slowly but easily trends to invasion and has a poor prognosis. In recent years domestic and foreign scholars have done a lot of researches about epithelial-mesenchymal transition(EMT) in SACC, for revealing the mechanism of its development, invasion and metastasis and exposing new therapy. This review elucidated the EMT mechanism in SACC