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-  2017 

破骨细胞蛋白酪氨酸磷酸酶与正畸移动牙牙根吸收的关系
The relationship between osteoclastic protein-tyrosine phosphatase and orthodontic treatment induced root resorption

DOI: 10.7518/gjkq.2017.01.018

Keywords: 牙根吸收,破骨细胞蛋白酪氨酸磷酸酶,作用机制,
root resorption
,osteoclastic protein-tyrosine phosphatase,mechanism of action

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Abstract:

摘要: 牙根吸收是正畸治疗过程中一种常见的并发症,影响正畸牙牙根吸收的因素十分复杂。牙根吸收的过程与骨吸收过程相似,由与破骨细胞形态相似功能相仿的破牙骨质细胞发挥主要作用。破骨细胞蛋白酪氨酸磷酸酶(PTP-oc)主要在破骨细胞中表达,且对破骨细胞具有正调节作用。本文探讨PTP-oc的作用机制,旨在为防治牙根吸收提供一定的参考依据。
Abstract: Root resorption is a common complication of orthodontic treatment whose factors are very complicated. The processe of root resorption is similar to bone resorption. The cementoclast plays a main role in this process, and it is similar to the shape and function of osteoclasts. Osteoclastic protein-tyrosine phosphatase(PTP-oc) is mainly expressed in osteoclasts, and has a positive regulatory effect on osteoclasts. In this paper, the mechanism of PTP-oc is discussed, which provides a reference for the prevention and treatment of root resorption.
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