巨噬细胞在骨组织修复中的研究进展
Research progress on macrophage in bone tissue repair

摘要： 免疫系统是人体的一道重要防线,参与其中的细胞包括B细胞、T细胞、DC细胞、巨噬细胞等,其中的巨噬细胞在组织损伤、肿瘤、骨改建等过程中起到尤为重要的作用,随着时间的推移,对于巨噬细胞的了解更为深入,但巨噬细胞与生物材料之间的应答仍有很多机理尚未明了。因此本综述主要探讨生物材料与巨噬细胞之间的应答,展望其潜在应用,为基础及临床研究提供新思路。
Abstract: The immune system is an important barrier for defense in the human body. This system includes B cells, T cells, dendritic cells (DC), and macrophages, which play a pivotal role in tissue injury, tumor, and bone remodeling. The understanding of macrophages has improved in the past years, but numerous mechanisms between macrophages and biomaterials remain largely unknown. Thus, the present study discusses the response between macrophages and biomaterials and predicts their potential application to provide new ideas for basic and clinical research.
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