唾液腺核素显像方法的优化

目的探讨唾液腺核素显像方法的优化。方法 对148例疑似干燥综合征(Sjgren's syndrome, SS)患者 进行唾液腺核素显像,其中58例用30分钟法,90例用15分钟法,以实验室检查作为对比组,临床诊断作为标准,分别进行统计学分析。结果 在灵敏度、特异度以及准确率30分钟法分别为97.62%(41/42)、26.67%(5/16)、78.95%(46/58),15分钟法为93.85%(61/65)、84.00%(21/25)、91.11%(82/90)。30分钟法与实验室检查提示特异度差异有统计学(P<0.05),15分钟法与实验室检查差异无统计学意义；30分钟法与15分钟法提示在特异度以及准确率上有统计学差异。结论 15分钟法能显著减少患者图像采集时间、提高检查准确率,值得在临床推广。
Objective To explore the optimization of salivary gland scintigraphy. Methods One hundred and forty eight patients with suspected Sjgren's syndrome(SS) underwent scintigraphic salivary gland imaging, including 59 cases using 30min method and 90 cases using 15min method. With clinical diagnosis as gold standard and laboratory results as controls, the sensitivity, specificity and accuracy of two scintigraphic methods were evaluated. Results The sensitivity, specificity, accuracy of 30min method were 97.62%(41/42),26.67%(5/16) and 78.95%(46/58); and those of 15min method were 93.85%(61/65),84.00%(21/25) and 91.11%(82/90), respectively. There were significant differences between 30min method and laboratory examination in specificity and sensibility (P<0.05); while no differences between 15min method and laboratory examination. There were also significant differences in specificity and accuracy between 30min method and 15min method. Conclusion Scintigraphy of salivary gland imaging with 15min method is more accurate and less time-consuming than that of 30min method in diagnosis of SS