辽宁省阜新市农村地区≥60岁老年人群不同年龄段血压控制最适值

目的 研究辽宁阜新农村地区≥60岁老年人群不同年龄段血压与不良结局发生的相关性,探讨不同年龄段血压控制最适值。方法 将纳入人群按60～69岁、≥70岁两个年龄段进行分层,采用Cox比例风险回归模型,在调整其他混杂危险因素后,探究不同年龄段血压与不良结局之间的关系。结果 60～69岁年龄段,相比参照组(收缩压120～129mmHg),收缩压<120mmHg或者≥140mmHg时,不良结局发生的风险性更高；≥70岁年龄段,相比参照组(收缩压130～139mmHg),收缩压<120mmHg或者≥150mmHg时,不良结局发生的风险性更高。60～69岁年龄段,相比参照组(舒张压80～89mmHg),舒张压<80mmHg或者≥90mmHg时,不良结局发生的风险险性更高；≥70岁年龄段,相比参照组(舒张压80～89mmHg),舒张压<80mmHg或者≥90mmHg时,不良结局发生的风险性更高。结论对于辽宁阜新农村地区≥60岁老年人群,60～69岁年龄段收缩压控制在120～139mmHg,舒张压控制在80～89mmHg,不良结局发生的风险性更低；≥70岁年龄段收缩压控制在120～149mmHg,舒张压控制在80～89mmHg,不良结局发生的风险性更低。
Objective To explore the optimal blood pressure (BP) among different age groups in population aged ≥60 years. Methods Total 8516 residents aged ≥60 years were selected from Fuxin rural area, including 4897 aged 60-69 and 3619 aged ≥70. After adjusting confounding factors, the relationships between BP and adverse outcomes were analyzed by Cox proportional hazards regression model. Results Compared with reference set of systolic blood pressure (SBP of 20-129mmHg), subjects aged 60 to 69 years with SBP<120mmHg or SBP≥140mmHg had a higher risk for adverse outcomes; subjects aged ≥70 years with SBP<120mmHg or SBP≥150mmHg had a higher risk for adverse outcomes compared with reference set (SBP of 130-139mmHg). For diastolic blood pressure (DBP), subjects both in 60～69 age group and ≥70 age group with DBP<80mmHg or DBP≥90mmHg had a higher risk for adverse outcomes compared with reference set (DBP of 80-90mmHg). Conclusion The study from Fuxin rural area indicates that if SBP could be controlled within 120-139mmHg, DBP could be controlled within 80-89mmHg, people in age group 60-69 years would have a lower risk of adverse cardiovascular outcomes; while for those in age group ≥70 years the SBP and DBP should be controlled to 120-149mmHg and 80～89mmHg, respectively