Component Analysis and Antifungal Activity of the Compounds Extracted from Four Brown Seaweeds with Different Solvents at Different Seasons Component Analysis and Antifungal Activity of the Compounds Extracted from Four Brown Seaweeds with Different Solvents at Different Seasons

The polar and nonpolar extracts of Colpomenia sinuosa,Padina pavonia,Cystoseira barbata and Sargassum vulgare collected during spring,summer and autumn were evaluated for their antifungal activities.The phytochemicals of unexplored seaweeds were analyzed by gas chromatography and mass spectrometric(GC/MS).The algal extracts were tested for their antifungal activities against Aspergillus niger,A.flavus,Penicillium parasiticus,Candida utilis and Fusarium solani.Phytochemicals were extracted from the four seaweeds with various solvents including methanol,ethanol,acetone,chloroform and dimethyl ether.Among the various extracts,methanolic extract showed the highest inhibition activity on all fungal species.Seasonal variation in antifungal activity was studied,while methanol extracts showed the best antifungal activity in spring.Cystoseira barbata was the most effective seaweed,having antifungal activity throughout the whole year.The UV-Vis phytochemical procedure and GC-MS analysis of the methanol extracts from tested species indicated the existence of different constituents.In conclusions,the compounds with antifungal activity were identified as indoles,terpenes,acetogenins,phenols,and volatile halogenated hydrocarbons