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- 2017
对肥胖与糖尿病之间分子机制的新认识
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Abstract:
随着社会经济的发展及生活水平的提高,肥胖和患糖尿病的人群迅速增加。肥胖与糖尿病之间有明 确的联系吗?其分子学机制有什么相关性?文章从肥胖与炎症水平、炎症因子白三烯B4(LTB4)与胰岛素敏感 性及胰岛素抵抗等方面,阐述LTB4在肥胖型2型糖尿病发生的始动作用和与糖尿病的相互关系。
With the development of social economy and the improvement of life quality, more and more people suffer from obesity and type 2 diabetes. Is there a clear correlation between obesity and type 2 diabetes? What is the molecular basis of the correlation? This article aimed to explain the relationship between obesity and inflammation, and the role of leukotriene B4 (LTB4) in insulin sensitivity and insulin resistance, thus analyzing the initiating effect of LTB4 on the development of obese type 2 diabetes