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- 2016
大叶性肺炎的起因推理
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Abstract:
大叶性肺炎是肺炎链球菌感染引起的全肺叶炎症,而肺炎链球菌存在于约一半的健康人的呼吸道。所以大叶性肺炎属于机会性的感染性疾病。在讲解大叶性肺炎的发病机制时,我们常用机体免疫力的下降来解释。但机体免疫力的降低是含义很笼统的说法,我们的疑问是,器官移植、肿瘤、糖尿病、艾滋病等多种疾病的患者,其机体的免疫力显著降低,为什么很少发生大叶性肺炎?从大叶性肺炎的诸多诱因来看,一个共性是体温降低。本文从体温降低诱发大叶性肺炎的角度分析其发病机制。
Lobar pneumonia is the lung inflammation caused by infection with Streptococcus pneumoniae overa whole lung lobe. While the Streptococcus pneumoniae is present in the respiratory tracts of around half of healthyindividuals, the incidence of lobar pneumonia is relatively rare. So the lobar pneumonia is in the category of opportunisticinfection. In explaining its pathogenesis, we often attribute it to the decline of immunity, but such a decline is unspecific inmeaning, as we can ask: regarding the patients with organ transplantation, cancer, diabetes, AIDS, etc, whose immunitiesare significantly weakened, why do they seldom suffer from lobar pneumonia? Judging from the multiple inducements ofthe lobar pneumonia, we found a common character, hypothermia. This paper is devoted to analyzing the pathogenesisfrom the perspective of hypothermia inducement