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-  2015 

普鲁兰多糖接枝共聚物作为药物载体的研究进展

Keywords: 普鲁兰多糖 共聚物 接枝 药物释放 进展
pullulan copolymer graft drug release advances

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Abstract:

接枝共聚改性是提高普鲁兰多糖性能的一种常用方法。通过改性修饰,能够扩展其应用范围,发挥产业化优势。本文从共聚材料的种类、普鲁兰多糖接枝共聚物的类型等角度,分别介绍了近年来作为药物载体的接枝改性普鲁兰多糖共聚物合成及在药物释放系统中的应用,对该领域未来的发展方向进行了展望,对产业化应用中应注意的问题提出了建议。
Graft copolymerization is one of the most effective methods to improve the performance of pullulan and extend its applications. This paper attempts to review the recent progresses in the preparation and application of graft copolymers of pullulan as pharmaceutical carriers from different synthesized polymers and the properties of graft copolymers of pullulan. The problems of pullulan based graft copolymers in drug release system are expounded, and the future development in this field direction is presented

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