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-  2017 

Prospect and Current Situation of Immune Checkpoint Inhibitors ?in First-line Treatment in Advanced Non-small Cell Lung Cancer Patients

DOI: : 10.3779/j.issn.1009-3419.2017.06.10

Keywords: PD-1/PD-L1 inhibitors, Lung neoplasms, First-line treatment

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Abstract:

With the breakthroughs achieved of programmed death-1 (PD-1)/PD-L1 inhibitors monotherapy as first-line and second-line treatment in advanced non-small cell lung cancer (NSCLC), the treatment strategy is gradually evolving and optimizing. Immune combination therapy expands the benefit population and improves the curative effect. A series of randomized phase III trials are ongoing. In this review, we discuss the prospect and current situation of immune checkpoint inhibitors in first-line treatment in advanced NSCLC patients.

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